Holoenzyme = Coenzyme + Cofactor

Apoenzyme = Holoenzyme + Coenzyme

Holoenzyme = Apoenzyme + Coenzyme

Coenzyme = Apoenzyme + Holoenzyme

Inactive form of enzymes

Active form of enzymes

Neutral form of enzymes

None of these

It decreases the $V_{max}$ without changing the $K_m$.

It increases the $K_m$ without changing the $V_{max}$.

It decreases both the $K_m$ and the $V_{max}$.

It increases both the $K_m$ and the $V_{max}$.

Acting as allosteric inhibitors

Stabilizing the enzyme's structure

Participating directly in the catalytic mechanism

Facilitating substrate binding

They are organic molecules.

They are not consumed during the reaction.

They are essential for the activity of some enzymes.

They are tightly bound to the enzyme.

Succinate dehydrogenase

Cytochrome c oxidase

ATP synthase

NADH dehydrogenase

Change in concentration of reactant or product per unit time

Amount of reactant or product at equilibrium

Difference in free energy between reactants and products

Temperature dependence of the equilibrium constant

I only

I and II

II and III

I and IV

$\frac{k_{cat}}{K_m}$

$k_{cat}$

$K_m$

$V_{max}$

Metabolites

Essential proteins

Enzymes

Receptors

Increase the rate

No effect

Denature the enzyme

Decrease the rate