The Question is from neet-botany cell-cycle-and-cell-division meiosis, and it was created by the author K SURESH KUMAR

Question

If a cell undergoing meiosis fails to divide its centromeres during a specific stage, which of the following processes would be directly affected?

K SURESH KUMAR · Accepted Answer

## CORE INFORMATION
✓ **Answer**: Option A
## CONCEPT FRAMEWORK
 **Primary Concept**: Meiosis and Chromosome Segregation
 **Related Topics**: Cell division, mitosis, anaphase, centromeres, sister chromatids, homologous chromosomes
 **Prerequisites**: Understanding of the stages of meiosis I and II, the role of centromeres in chromosome segregation.
## SOLUTION PATHWAY
**Given Information**:
  A cell undergoing meiosis fails to divide its centromeres during a specific stage.
  We need to identify the process directly affected by this failure.
**Method & Steps**:
 1. **Understanding Centromere Function**: Centromeres are crucial for chromosome segregation. They are the attachment points for spindle fibers, which pull sister chromatids apart during anaphase.
  Reasoning:  If centromeres don't divide, sister chromatids remain attached.
  Formula/Rule: N/A
 2. **Analyzing Meiotic Stages**: Meiosis I separates homologous chromosomes, while Meiosis II separates sister chromatids.
  Working:  The failure to separate centromeres directly prevents the separation of sister chromatids.
  Key Point:  The failure would affect a stage where sister chromatids are supposed to separate.
 3. **Identifying the Affected Stage**:  Anaphase II is the stage where sister chromatids are pulled apart to opposite poles of the cell.
  Result: The failure to divide centromeres directly affects the segregation of sister chromatids during Anaphase II.
  Verification:  The other options are indirectly affected or not affected at all.
 ## OPTION ANALYSIS
A] ✓: **Segregation of sister chromatids during Anaphase II**: This is correct because the centromere is the point of attachment for sister chromatids, and its failure to divide prevents their separation during Anaphase II.
B] :x: **Pairing of homologous chromosomes during Prophase I**: Homologous chromosome pairing happens in Prophase I, and centromere division is not directly involved in this process.
C] :x: **Formation of the spindle apparatus**: While the spindle apparatus is essential for chromosome segregation, the failure of centromere division doesn't directly prevent its formation; it affects the *function* of the spindle.
D] :x: **Condensation of chromosomes during Prophase I**: Chromosome condensation occurs in Prophase I, independent of centromere division.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing meiosis I and meiosis II: Remember that homologous chromosomes separate in meiosis I, and sister chromatids separate in meiosis II.
  How to avoid:  Carefully review the events of each meiotic stage.
  2.Focusing on indirect effects: The question asks for the *directly* affected process. Other processes might be affected indirectly but not directly due to the centromere failure.
  How to avoid:  Focus on the immediate consequence of the centromere not dividing.
 **Quick Tips**:
  1.Visualize meiosis: Drawing diagrams of meiosis I and II can help you visualize the role of centromeres.
  2.Remember the key function: The primary function of the centromere is to attach sister chromatids and allow their separation.

K SURESH KUMAR · Answer

The correct Option is "Segregation of sister chromatids during Anaphase II"

K SURESH KUMAR · Answer

Pairing of homologous chromosomes during Prophase I

K SURESH KUMAR · Answer

Formation of the spindle apparatus

K SURESH KUMAR · Answer

Condensation of chromosomes during Prophase I

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