The Question is from neet-botany cell-cycle-and-cell-division , and it was created by the author Mr. NARESH KUMAR K

Question

Which of the following events does NOT occur during prometaphase of mitosis?

Mr. NARESH KUMAR K · Accepted Answer

## CORE INFORMATION
✓ **Answer**: D
## CONCEPT FRAMEWORK
 **Primary Concept**: Mitosis and its phases
 **Related Topics**: Cell cycle, chromosomes, microtubules, nuclear envelope
 **Prerequisites**: Basic understanding of cell division and mitosis stages.
## SOLUTION PATHWAY
**Given Information**:
The question asks to identify the event that does NOT happen during prometaphase of mitosis.
**Method & Steps**:
1. **Understanding Prometaphase**: Prometaphase is a transitional stage between prophase and metaphase in mitosis.  Key events include the breakdown of the nuclear envelope, the attachment of kinetochore microtubules to chromosomes, and the movement of chromosomes towards the metaphase plate.
2. **Analyzing Options**: Let's examine each option:
    * **A: Breakdown of the nuclear envelope:** This is a hallmark of prometaphase. The nuclear envelope fragments, allowing microtubules to access the chromosomes.
    * **B: Attachment of kinetochore microtubules to chromosomes:** Kinetochores, protein structures on chromosomes, bind to microtubules during prometaphase, facilitating chromosome movement.
    * **C: Movement of chromosomes towards the metaphase plate:**  Chromosomes begin their migration towards the metaphase plate (the equatorial plane of the cell) during prometaphase.
    * **D: Replication of the centrosomes:** Centrosome duplication occurs during the S phase (synthesis phase) of the cell cycle, well before prometaphase.  Centrosomes are already duplicated by the time prometaphase begins.
3. **Final step**: The only event that does not occur during prometaphase is the replication of centrosomes. 
  Result: D
  Verification:  The other options are all critical events of prometaphase.
 ## OPTION ANALYSIS
A ✓: Breakdown of the nuclear envelope is a defining characteristic of prometaphase.
B :x: Attachment of kinetochore microtubules is crucial for chromosome movement in prometaphase.
C :x: Chromosome movement towards the metaphase plate is a key event of prometaphase.
D :x: Centrosome replication happens much earlier in the cell cycle, during interphase.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing prometaphase events with those of other mitotic phases: Carefully review the events of each phase to avoid this.
  2.Assuming centrosome replication happens during prometaphase: Remember that centrosome duplication is a prior event.
 **Quick Tips**:
  1.Visualize the stages of mitosis: Use diagrams or animations to understand the chronological order of events.
  2.Create a summary table:  List the key events for each phase of mitosis to improve retention.

Mr. NARESH KUMAR K · Answer

Breakdown of the nuclear envelope

Mr. NARESH KUMAR K · Answer

Attachment of kinetochore microtubules to chromosomes

Mr. NARESH KUMAR K · Answer

Movement of chromosomes towards the metaphase plate

Mr. NARESH KUMAR K · Answer

The correct Option is "Replication of the centrosomes"

NEET Botany Cell Cycle and Cell Division MCQs

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