A mutation in the gene encoding for 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) results in apparent mineralocorticoid excess (AME). This is because:
Aldosterone production is increased.
Cortisol is not converted to cortisone in the kidney, allowing it to bind to mineralocorticoid receptors.
The kidneys become insensitive to aldosterone.
Sodium reabsorption in the kidneys is inhibited.
Related Questions
Chemicals which are synthesized by one organism and affect the behaviour of another member of the same species, are called
Enzymes
Hormones
Flavoids
Pheromones
Which of the following is correct
Leukaemia - Skin cancer
Diabetes - Sugar free
Rheumatic fever - Defective pacemaker
Heart attack - Radiation therapy
A rare tumor of the adrenal medulla secretes excessive amounts of catecholamines. Which physiological responses would be observed in a patient with this tumor?
Decreased heart rate, decreased blood pressure, and hypoglycemia
Increased heart rate, elevated blood pressure, and hyperglycemia
Decreased heart rate, elevated blood pressure, and hyperglycemia
Increased heart rate, decreased blood pressure, and hypoglycemia
Which hormone is responsible for regulating blood sugar levels?
Adrenaline
Thyroxine
Insulin
Growth hormone
Heterocrine glands are the glands, which
Work as exocrine glands
Work as endocrine glands
Have dual (exo and endocrine) mode of function
Are present in the hypothalamus region of brain
Which hormone deficiency is most strongly associated with the development of osteoporosis?
Thyroxine
Estrogen
Growth Hormone
Insulin
Which of the following pairs correctly matches a hormone with its amino acid precursor?
Melatonin - Tyrosine
Thyroxine - Tryptophan
Epinephrine - Tyrosine
Serotonin - Tyrosine
I. Non-nutrient, II. Intercellular messenger, III. Produced in trace amount, IV. Intracellular messenger. Select the correct properties of hormones from above list and then choose the option correct combination
I, II and III
II, III and IV
I, II and IV
I, III and IV
I. Somatostatin inhibits intestinal absorption of glucose, II. Leydig’s cell secrete progesterone, III. Melatonin is secreted by pineal gland, IV. Myxoedema is a thyroid disorder, V. Neurohypophysis secreteS ACTH . Select the correct statements and choose the option
I, III and IV
II, III and V
I, IV and V
II, IV and V
Hormones provides coordination in
Vertebrates
Invertebrates
Both (a) and (b)
None of these