1.

    A mutation in the gene encoding for 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) results in apparent mineralocorticoid excess (AME). This is because:

    A

    Aldosterone production is increased.

    B

    Cortisol is not converted to cortisone in the kidney, allowing it to bind to mineralocorticoid receptors.

    C

    The kidneys become insensitive to aldosterone.

    D

    Sodium reabsorption in the kidneys is inhibited.

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    3.

    A rare tumor of the adrenal medulla secretes excessive amounts of catecholamines. Which physiological responses would be observed in a patient with this tumor?

    A

    Decreased heart rate, decreased blood pressure, and hypoglycemia

    B

    Increased heart rate, elevated blood pressure, and hyperglycemia

    C

    Decreased heart rate, elevated blood pressure, and hyperglycemia

    D

    Increased heart rate, decreased blood pressure, and hypoglycemia

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    5.

    Heterocrine glands are the glands, which

    A

    Work as exocrine glands

    B

    Work as endocrine glands

    C

    Have dual (exo and endocrine) mode of function

    D

    Are present in the hypothalamus region of brain

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