Which specific type of chromosomal translocation is MOST frequently associated with chronic myeloid leukemia (CML), and what are the resulting fusion gene and its protein product?
t(8;14); MYC-IGH; Transcription factor.
t(14;18); BCL2-IGH; Anti-apoptotic protein.
t(9;22); BCR-ABL; Tyrosine kinase.
t(15;17); PML-RARA; Retinoic acid receptor.
Related Questions
Which one of the following non-infectious disease is the major cause of death in humans?
Cancer
AIDS
Asthma
Typhoid
Which cellular process is MOST directly affected by mutations that lead to uncontrolled cell growth in cancer?
Protein synthesis
Cellular respiration
Cell cycle regulation
Active transport
Hybridomas are the fusion product of
Normal antibody producing cell with myeloma
Abnormal antibody producing cell with myeloma
Sex cells with myeloma
Bone cells with myeloma
Cells obtained from cancerous tumours are known as
Normal cells
Tumor cells
Stem cells
Blood cells
Cancerous cells spread through
Lymph
Blood
Secondary growths of malignant tumour
All of the above
Which of the following causes cancer of vagina?
Cadmium oxide
Diethyl stilbestrol
Aflatoxin
Vinyl chloride
Proliferation of cancer cells is not limited because of
Loss of cell cycle control and evasion of apoptosis
Increased cellular differentiation and specialization
Enhanced contact inhibition and growth factor dependence
Limited access to nutrients and oxygen
What is the primary function of oncogenes?
Suppress cell growth and division
Promote cell growth and division
Trigger apoptosis
Repair damaged DNA
Read the given statements
Statement-A : HIV is an oncogenic virus.
Statement-B : Non-cancerous cells exhibit contact inhibition.
Statement-C : Malignant tumors do not show metastasis and angiogenesis.
Choose the correct option.
Statements B and C are correct; Statement A is incorrect
Statements B and C are incorrect; Statement A is correct
Statements A and C are correct; Statement B is incorrect
Statements A and B are correct; Statement C is incorrect
Which one of the following statements is correct?
Patients, who had undergone surgery are given cannabinoids to relieve pain
Benign tumours show the property of metastasis
Heroin accelerates body functions
Malignant tumours may exhibit metastasis
