Explain the concept of “Warburg effect” in cancer cells and its implication in cancer diagnosis and therapy.
Decreased glucose uptake and oxidative phosphorylation; MRI scan; Targeting DNA repair mechanisms.
Increased glucose uptake and preferential lactic acid fermentation even in the presence of oxygen; PET scan using FDG; Targeting metabolic pathways.
Increased lipid synthesis and beta-oxidation; CT scan; Targeting growth factor receptors.
Decreased amino acid uptake and protein synthesis; Ultrasound; Targeting cell cycle checkpoints.
Related Questions
Transformation of normal cell cancerous cell is induced by
Carcinogens
UV-rays
Neoplastic cells
Mutagens
Cells obtained from cancerous tumours are known as
Normal cells
Tumor cells
Stem cells
Blood cells
Consider the following statements
I. The property of metastasis is shown by malignant tumours
II. Carcinogens are the agents that causes cancer
III. Benign tumour causes little damage to body cells
Which of the statements given above are correct?
I and II
I and III
II and III
I, II and III
What is the primary function of oncogenes?
Suppress cell growth and division
Promote cell growth and division
Trigger apoptosis
Repair damaged DNA
Normal cell have genes called …A… which are present in inactiveated state but under certain conditions like …B… they get transformed to …C… Here A, B and C refers to
A- Proto-oncogenes, B- Exposure to carcinogens/radiation, C- Oncogenes
A- Oncogenes, B- Viral infections, C- Proto-oncogenes
A- Tumor suppressor genes, B- DNA damage, C- Mutated tumor suppressor genes
A- Growth factors, B- Hormonal imbalance, C- Activated growth factors
Select the true statements
I. Cancer can be detected by the use of antibodies against cancer specific antigens for certain type of cancer
II. The tumour cells are surgically removed to reduce the load of cancerous cells
III. Certain chemotherapeutic drugs are used to kill the cancerous cells, but majority of the drugs have side affects like hair loss, anaemia, etc.
I and II
I and III
II and III
I, II and III
Cell division or mitosis is normal process in a living cell, but sudden and abnormal mitosis in an organ will frequently result in
Zygote
Cancer
New organ
Gastrula
Which one of the following non-infectious disease is the major cause of death in humans?
Cancer
AIDS
Asthma
Typhoid
Pick Out correct statement
More than 10 million Indian suffer from cancer
Cancer cells shows contact inhibition
Benign tumors not confined to original location
Malignant tumors cells called neoplastic or tumors cells
Hodgkins disease is
Cancer of the lymphoid tissue
Cancer of the mammary gland
cancer of the WBC
Cancer of the liver
