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    2.

    A genetic mutation affects the $Ca^{2+}$$-ATPase pumps in the sarcoplasmic reticulum (SR). Which of the following would be the MOST likely direct consequence of this mutation in muscle fibers?

    A

    Inhibition of action potential propagation along the sarcolemma

    B

    Reduced release of acetylcholine at the neuromuscular junction

    C

    Prolonged muscle contraction due to impaired $Ca^{2+}$$ removal from the sarcoplasm

    D

    Inability of troponin to bind $Ca^{2+}$$

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    8.

    Calcium is important in skeletal muscle contraction because it

    A

    Prevents the formation of bonds between the myosin cross bridge and the actin filament.

    B

    Binds to troponin to remove the masking of active sites on actin myosin

    C

    Detaches the myosin head from the actin filament.

    D

    Activates the myosin ATPase by Binding to it.

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    9.

    What happens immediately after the power stroke in the cross-bridge cycle?

    A

    ATP binds to the myosin head.

    B

    The myosin head reattaches to actin.

    C

    Calcium ions are released from the sarcoplasmic reticulum.

    D

    Acetylcholine is released into the synaptic cleft.

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