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Which of the following is NOT associated with muscle contraction?
Release of calcium ions from the sarcoplasmic reticulum
Binding of calcium ions to troponin
Sliding of actin filaments over myosin filaments
Depolymerization of microtubules
A patient presents with muscle weakness and fatigue. Biochemical analysis reveals a defect in the calcium-binding protein crucial for muscle contraction, specifically within the thin filaments. Which protein is MOST likely affected?
Tropomyosin
Troponin T
Troponin I
Troponin C
A researcher is studying muscle contraction in vitro. They observe that even with sufficient ATP and $Ca^{2+}$$, contraction doesn't occur when they introduce a compound that specifically inhibits the binding of myosin heads to actin filaments. Which step of the cross-bridge cycle is directly affected by this compound?
Release of Pi from the myosin head
Attachment of myosin heads to actin
Hydrolysis of ATP
Power stroke
In a skeletal muscle fiber, during a single twitch, the amount of tension generated during the contraction phase is directly proportional to:
The concentration of ATP in the sarcoplasm
The duration of the action potential
The frequency of nerve stimulation
The number of cross-bridges formed between actin and myosin
During muscle contraction, the conformational change in the myosin head that leads to the power stroke is primarily driven by:
Hydrolysis of ATP
Binding of ATP
Release of inorganic phosphate (Pi)
Binding of Calcium ions to troponin
What protein filaments slide past each other during muscle contraction?
Actin and Myosin
Actin and Tropomyosin
Myosin and Troponin
Troponin and Tropomyosin
The sliding filament theory explains the mechanism of:
Nerve impulse transmission
Muscle contraction
Bone growth
Hormone secretion
During muscle contraction, the cross-bridge cycle is initiated by the binding of which molecule to troponin?
Calcium ions
ATP
Acetylcholine
Sodium ions
In the sliding filament theory of muscle contraction, which of the following shortens during contraction?
Actin filaments
Myosin filaments
Sarcomere
A-band
The sliding filament theory explains the mechanism of which type of movement?
Ciliary
Amoeboid
Muscular
Flagellar