The Question is from neet-zoology structural-organisation-in-animals epithelial-tissue, and it was created by the author T HARITHA

Question

Which statement regarding the basal lamina of epithelial tissue is INCORRECT?

T HARITHA · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
	**Primary Concept**: Structure and function of the basal lamina
	**Related Topics**: Epithelial tissue, extracellular matrix, cell adhesion
	**Prerequisites**: Basic histology and cell biology
## SOLUTION PATHWAY
**Given Information**:
	The question asks for the INCORRECT statement about the basal lamina.
**Method & Steps**:
	1. Analyze each option based on the known functions and composition of the basal lamina.
	2. Identify the statement that contradicts established knowledge.
	3. Confirm the correct answer by verifying the accuracy of the other options.
 ## OPTION ANALYSIS
[A] ✓: It influences cell polarity. The basal lamina provides a structural foundation for epithelial cells and plays a crucial role in establishing and maintaining their apical-basal polarity.
[B] ✓: It regulates cell proliferation and differentiation. The basal lamina interacts with cell surface receptors and influences signaling pathways that control cell growth and differentiation.
[C] :x: It is rich in reticular fibers. This statement is incorrect. While the underlying connective tissue contains reticular fibers which form the reticular lamina, the basal lamina itself is primarily composed of type IV collagen, laminin, entactin/nidogen, and perlecan (heparan sulfate proteoglycan), not reticular fibers (type III collagen).
[D] ✓: It acts as a selective filter for molecules. The basal lamina acts as a barrier regulating the passage of molecules between the epithelium and underlying connective tissue.
 ## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing the basal lamina with the basement membrane: The basement membrane is visible under a light microscope and is composed of the basal lamina and the reticular lamina. The basal lamina is only visible with an electron microscope.
		2. Overlooking the role of the basal lamina in cell signaling:  The basal lamina is not just a structural support, it actively participates in cellular processes.
	**Quick Tips**:
		1. Remember the acronym 'CLEN' to recall the main components of the basal lamina: Collagen IV, Laminin, Entactin/Nidogen, and Perlecan.
		2. Visualize the basal lamina as a dynamic interface between the epithelium and connective tissue, influencing various cellular activities.

T HARITHA · Answer

It influences cell polarity.

T HARITHA · Answer

It regulates cell proliferation and differentiation.

T HARITHA · Answer

The correct Option is "It is rich in reticular fibers."

T HARITHA · Answer

It acts as a selective filter for molecules.

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