The Question is from neet-botany biological-classification , and it was created by the author B VENKAT

Question

Which of the following statements is INCORRECT regarding prions?

B VENKAT · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
 **Primary Concept**: Prion biology and characteristics
 **Related Topics**: Neurodegenerative diseases, protein misfolding, sterilization techniques
 **Prerequisites**: Basic understanding of proteins, diseases, and sterilization methods.
## SOLUTION PATHWAY
**Given Information**:
  Four statements regarding prions.
  Need to identify the incorrect statement.
**Method & Steps**:
 1. Analyze each statement individually to determine its accuracy regarding prion properties.
  Reasoning: Prions are infectious agents composed of misfolded proteins. They are known for their resistance to degradation and their ability to induce misfolding in other proteins.
 2. Evaluate the correctness of each statement based on established prion biology.
  Working: 
        A. Prions are resistant to proteases (enzymes that break down proteins). This is TRUE.
        B. Prions cause neurodegenerative diseases (e.g., Creutzfeldt-Jakob disease). This is TRUE.
        C. Prions are easily destroyed by standard sterilization techniques. This is FALSE. Standard sterilization techniques are often ineffective against prions due to their resilience.
        D. Prions can exist in multiple conformational states (normal and misfolded). This is TRUE.
 3. Identify the incorrect statement.
  Result: Statement C is incorrect.
  Verification: The resilience of prions to standard sterilization methods is a well-established fact.
 ## OPTION ANALYSIS
A ✓: Prions are indeed resistant to proteases, making them difficult to degrade.
B :x: Prions are the causative agents of several neurodegenerative diseases.
C :x: This is the incorrect statement. Prions are notoriously resistant to standard sterilization techniques, requiring specialized methods for inactivation.
D :x: Prions exist in at least two conformational states: a normal, cellular form and an abnormal, infectious form.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing prions with viruses or bacteria: Prions are unique infectious agents composed solely of proteins, unlike viruses and bacteria.
  2.Overestimating the effectiveness of standard sterilization techniques against prions: Standard sterilization methods often fail to eliminate prions.
 **Quick Tips**:
  1.Remember the key characteristics of prions: resistance to proteases, heat, and radiation.
  2.Associate prions with neurodegenerative diseases such as Creutzfeldt-Jakob disease, Kuru, and bovine spongiform encephalopathy.

B VENKAT · Answer

They are resistant to proteases.

B VENKAT · Answer

They cause neurodegenerative diseases.

B VENKAT · Answer

The correct Option is "They are easily destroyed by standard sterilization techniques."

B VENKAT · Answer

They can exist in multiple conformational states.

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