1.

    A transgenic mouse expressing a human growth hormone gene exhibits gigantism. Researchers discover a second transgenic mouse line with the same human growth hormone gene construct, yet these mice show normal growth. Which of the following is the MOST LIKELY explanation for this discrepancy?

    A

    The second mouse line has a mutation in the mouse growth hormone receptor gene.

    B

    The human growth hormone gene is not being transcribed in the second mouse line.

    C

    Position effect variegation due to the transgene's insertion site in the second mouse line.

    D

    The second mouse line expresses an endogenous inhibitor of human growth hormone.

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    4.

    In cloning of cattle, a fertilized egg is taken out of the mother’s womb and

    A

    The egg is divided into four pairs of cells, which are implanted into the womb of other cows

    B

    In the eight cell stage, cells are separated and cultured until small embryos are formed, which are implanted into the womb of other cows

    C

    In the eight cell stage, the individual cells are separated under electrical field for further development in culture media

    D

    From this upto eight identical twins can be produced

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    8.

    A transgenic mouse expressing a human growth hormone gene exhibits gigantism. Researchers discover a second transgenic mouse line with the same human growth hormone gene construct, yet these mice show normal growth. Which of the following is the MOST LIKELY explanation for this discrepancy?

    A

    The second mouse line has a mutation in the mouse growth hormone receptor gene.

    B

    The human growth hormone gene is not being transcribed in the second mouse line.

    C

    Position effect variegation due to the transgene's insertion site in the second mouse line.

    D

    The second mouse line expresses an endogenous inhibitor of human growth hormone.

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