Histone proteins are rich in which of the following amino acids?
Lysine and Arginine
Glycine and Alanine
Tryptophan and Phenylalanine
Cysteine and Methionine
Related Questions
The large puffs on polytene chromosomes, known as Balbiani rings, are primarily involved in:
RNA synthesis
DNA replication
Protein degradation
Chromosome condensation
The presence of histone H1 in association with a nucleosome suggests:
Further compaction of chromatin structure
Transcription activation
DNA replication initiation
Nucleosome disassembly
Certain histone modifications are associated with actively transcribed genes. Which of the following combinations is MOST likely to be found in the nucleosomes of such genes?
Methylation of H3K9 and H3K27; Deacetylation of H3 and H4
Phosphorylation of H2AX; Trimethylation of H3K9
Acetylation of H3 and H4; Trimethylation of H3K4
Ubiquitination of H2A; Trimethylation of H3K27
During cell division, spindle fibers attach to which specific structure on the chromosomes?
Centromere
Telomere
Chromatid
Kinetochore
Failure of spindle fibers to attach correctly to the kinetochores can result in:
Normal cell division
Apoptosis
Nondisjunction
Interphase arrest
Polytene chromosomes, found in certain insect tissues, exhibit distinct banding patterns. These bands represent:
Individual genes arranged linearly along the chromosome.
Regions of heterochromatin exclusively.
Regions where DNA replication has been halted prematurely.
Regions of highly condensed chromatin corresponding to inactive genes interspersed with less condensed regions of active genes.
Which of the following processes is facilitated by the binding of histone H1 to a nucleosome?
DNA unwinding
Chromatin condensation
RNA splicing
Protein synthesis
When the Centrometre is situated in the middle of two equal arms of chromosomes, the chromosome is referred as:
Sub-metacentric
Acrocentric
Metacentric
Telocentric
Approximately how many base pairs of DNA are wrapped around a histone octamer in a nucleosome?
20
146
200
1000
The 'histone code' hypothesis proposes that specific combinations of histone modifications influence gene expression. If a researcher discovered a novel histone modification, which experimental approach would be LEAST informative for initially investigating its potential role in gene regulation?
Analyzing the genome-wide distribution of the modification using ChIP-seq.
Correlating the presence of the modification with gene expression levels.
Assessing the binding of specific regulatory proteins to the modified histone.
Determining the crystal structure of the modified histone.
