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NEET Questions / Botany / Respiration in Plants / Glycolysis
Under anaerobic conditions, if a cell utilizes glucose exclusively via glycolysis, what would be the net ATP yield per glucose molecule if the glyceraldehyde-3-phosphate dehydrogenase reaction is bypassed by a hypothetical enzyme that directly converts glyceraldehyde-3-phosphate to 3-phosphoglycerate without generating NADH?
0 ATP
2 ATP
4 ATP
6 ATP
A rare genetic disorder impairs the enzyme phosphoglycerate kinase. Which of the following metabolic consequences is MOST likely to be observed in an individual with this disorder?
Increased ATP production and accumulation of 3-phosphoglycerate
Reduced ATP production and accumulation of 1,3-bisphosphoglycerate
No change in ATP production but accumulation of pyruvate
Increased lactate production and depletion of NAD+
In a hypothetical scenario, a cell has a mutated form of aldolase that cleaves fructose 1,6-bisphosphate into two molecules of dihydroxyacetone phosphate. How many net ATP molecules would be produced from one molecule of glucose under anaerobic conditions in this cell?
0 ATP
2 ATP
4 ATP
6 ATP
If the standard free energy change (') for the conversion of glucose to pyruvate is -180 kJ/mol and the ' for ATP hydrolysis is -30 kJ/mol, what is the theoretical maximum number of ATP molecules that could be generated from the complete oxidation of one glucose molecule to pyruvate, assuming 100% efficiency?
3 ATP
6 ATP
9 ATP
12 ATP
Arsenic poisoning can inhibit several enzymes, including lipoic acid-containing enzymes like pyruvate dehydrogenase. How would arsenic poisoning indirectly affect glycolysis?
Arsenic directly inhibits hexokinase, the first enzyme in glycolysis.
Arsenic enhances glycolysis by stimulating phosphofructokinase activity.
By inhibiting pyruvate dehydrogenase, arsenic poisoning would lead to a buildup of pyruvate, which could in turn inhibit glycolysis through feedback mechanisms.
Arsenic has no effect on glycolysis as it specifically targets mitochondrial enzymes.
Imagine a scenario where a cell expresses a mutated form of glyceraldehyde-3-phosphate dehydrogenase that uses inorganic phosphate but does not reduce NAD+ to NADH. What is the fate of the high-energy phosphate group acquired during this altered reaction in the subsequent steps of glycolysis under anaerobic conditions?
It is lost as inorganic phosphate during the conversion to 2-phosphoglycerate.
It is transferred to ADP to form ATP by phosphoglycerate kinase.
It remains attached to the 3-carbon molecule and is ultimately incorporated into lactate.
It is used to phosphorylate another glucose molecule, priming it for entry into glycolysis.
Which of the following is the net gain of ATP molecules from one molecule of glucose during glycolysis?
1 ATP
2 ATP
3 ATP
4 ATP
Where does glycolysis occur within the cell?
Mitochondria
Nucleus
Cytoplasm
Golgi apparatus
Which of the following is the end product of glycolysis?
Glucose
Acetyl CoA
Pyruvate
Lactate