A rare genetic disorder affects the blood-testis barrier, specifically compromising the tight junctions between Sertoli cells. Which of the following is the MOST likely consequence of this compromised barrier?
Increased testosterone production
Enhanced spermatogenesis
Autoimmune response against developing sperm
Premature release of immature sperm
Related Questions
Development of epididymis, vas deference, seminal vesicles, prostate glands and urethra is controlled by
Estrogen
Progesterone
Androgen
Pituitary hormone
Compared to a bull, a bullock is docile because of
Higher levels of thyroxine
Higher levels of cortisone
Lower levels of blood testosterone
Lower levels of adrenaline/ noradrenaline in its blood
The descent of the testes into the scrotum normally occurs:
At puberty
During fetal development
After birth
During adolescence
Compared to a bull, a bullock is docile because of
Higher levels of thyroxine
Higher levels of cortisone
Lower levels of blood testosterone
Lower levels of adrenaline/ noradrenaline in its blood
Cryptorchidism is a condition characterized by:
Inflammation of the testes
Undescended testes
Enlarged prostate
Low sperm count
The Leydig cells or …A… cells which are present in …B… . Spaces produce a group of hormone called androgens mainly …C…
Choose the correct option for A, B and C
A- Interstitial, B- Interstitial spaces, C- Testosterone
A- Sertoli, B- Seminiferous tubules, C- Estrogen
A- Interstitial, B- Germinal epithelium, C- Progesterone
A- Sertoli, B- Epididymis, C- Inhibin
During the development of the male reproductive system, the testis-determining factor (TDF) initiates the differentiation of the indifferent gonad into a testis. Which of the following accurately describes the subsequent cascade of events related to testicular descent?
Sertoli cells produce testosterone, stimulating Wolffian duct development, while Leydig cells produce AMH, causing Müllerian duct regression. Testicular descent is independent of hormonal influence.
Leydig cells produce both testosterone and AMH, leading to Wolffian duct development and Müllerian duct regression, respectively. INSL3 inhibits testicular descent until puberty.
Sertoli cells produce AMH, leading to Müllerian duct regression, followed by testosterone production by Leydig cells, promoting Wolffian duct development. INSL3 mediates transabdominal testicular descent, and androgens contribute to the inguinoscrotal phase.
Testosterone production precedes AMH production, and both are secreted by Leydig cells. The gubernaculum pulls the testes into the abdomen, and INSL3 initiates their descent into the scrotum.
Which cells in the testis are responsible for the production of testosterone?
Sertoli cells
Leydig cells
Spermatogonia
Spermatids
Spermatogenesis is under the regulatory influence of
ADH
FSH
LH
STH
Androgens act on the …A… and influence the male sexual behavior called …B… . These hormones produce …C… effect on protein and carbohydrate metabolism. Choose the correct combination of A, B and C
Nervous system, Libido, Anabolic
Endocrine system, Menstruation, Catabolic
Circulatory system, Fertilization, Metabolic
Digestive system, Lactation, Anaerobic
