A rare genetic disorder affects the sodium-glucose cotransporter SGLT2 in the proximal convoluted tubule, rendering it non-functional. Which of the following would be the MOST prominent consequence?
Metabolic alkalosis
Increased water reabsorption
Increased glucose excretion in urine
Decreased sodium excretion in urine
Related Questions
GFR (Glomerular Filtration Rate) is the amount of filtrate formed by the kidney per
Hour
Second
Minute
10 seconds
Choose the correct ones: I. Vasa recta is lacking in cortical nephrons, II. Maximum number of nephrons in kidney are juxta-medullary type, III. DCT of many nephorns open into collecting tubule, IV. During summer when body loses lot of water by evaporation, the release of ADH is suppressed, V. When someone drinks lot of water, ADH release is suppressed, VI. Exposure to cold temperature stimulates ADH release, VII. An increase in glomerular blood flow stimulates formation of angiotensin II. The correct option is
I, II and III
III, IV and V
III, V and VI
IV, V and VI
A fall in the GFR rate activates the
JG cells to release renin
JG cells to release aldosterone
JG cells to release epinephrine
JG cells to release nor-epinephrine
Choose the correct ones: I. Vasa recta is lacking in cortical nephrons, II. Maximum number of nephrons in kidney are juxta-medullary type, III. DCT of many nephorns open into collecting tubule, IV. During summer when body loses lot of water by evaporation, the release of ADH is suppressed, V. When someone drinks lot of water, ADH release is suppressed, VI. Exposure to cold temperature stimulates ADH release, VII. An increase in glomerular blood flow stimulates formation of angiotensin II. The correct option is
I, II and III
III, IV and V
III, V and VI
IV, V and VI
The urine is
Hypotonic to blood and isotonic in medullarly fluid
Hypertonic to blood and isotonic to medullarly fluid
Isotonic to blood and hypotonic to medullarly fluid
Isotonic to blood and hypertonic to medullarly fluid
Which of these is NOT a component of the nephron?
Glomerulus
Bowman's capsule
Loop of Henle
Ureter
Choose the false statement
Tubular cells secretes , and Ammonia to filtrate
Tubular cells helps to maintain the acid base balance of the body fluid
Tubular cells helps in ionic balance
Tubular secretion is not very important step in urine formation
Glomerular filtrate is
Blood minus blood corpuscles and plasma protein
Blood minus corpuscles
Mixture of water, ammonia and corpuscles
Urine
Specific gravity of urine normally is
1.010-1.015
1.015-1.020
1.020-1.025
Both (a) and (b)
If Henle’s loop were absent from mammalian nephron, which of the following is to be expected?
The urine will be more concentrated
The urine will be more dilute
There will be no urine formation
There will be hardly any change in the quality and quantity of urine formed
