The Question is from neet-zoology excretory-products-and-their-elimination , and it was created by the author T HARITHA

Question

A patient presents with glucosuria, but their blood glucose levels are normal.  Further investigation reveals a defect in the reabsorption of glucose. Which part of the nephron is most likely affected?

T HARITHA · Accepted Answer

## CORE INFORMATION
✓ **Answer**: A
## CONCEPT FRAMEWORK
 **Primary Concept**: Renal Physiology, specifically glucose reabsorption in the nephron.
 **Related Topics**: Nephron structure and function, tubular reabsorption, glucosuria.
 **Prerequisites**: Understanding of the nephron's different segments and their roles in urine formation.
## SOLUTION PATHWAY
**Given Information**:
  * Glucosuria (glucose in the urine).
  * Normal blood glucose levels.
  * Defect in glucose reabsorption.
**Method & Steps**:
 1. Identify the nephron segment responsible for glucose reabsorption.
  Reasoning: Glucose is freely filtered in the glomerulus.  Almost all filtered glucose is normally reabsorbed, preventing its excretion in the urine.  The presence of glucosuria with normal blood glucose indicates a problem with this reabsorption process.
  Formula/Rule:  None directly applicable, this is a qualitative understanding question.
 2. Determine which nephron segment is primarily involved in glucose reabsorption.
  Working: The proximal convoluted tubule (PCT) is the primary site of glucose reabsorption.  It utilizes sodium-glucose cotransporters (SGLTs) to actively transport glucose from the filtrate into the peritubular capillaries.
  Key Point:  While some glucose reabsorption might occur in other segments, it's insignificant compared to the PCT.
 3. Conclude which part of the nephron is most likely affected.
  Result: Proximal Convoluted Tubule (PCT).
  Verification: A defect in the PCT's glucose reabsorption mechanisms would explain the presence of glucosuria despite normal blood glucose levels.
 ## OPTION ANALYSIS
[A] ✓: Proximal Convoluted Tubule (PCT): This is correct because the PCT is the primary site of glucose reabsorption. A defect here would lead to glucosuria even with normal blood glucose.
[B] :x: Distal Convoluted Tubule (DCT): While the DCT plays a role in fine-tuning electrolyte balance, it's not the primary site of glucose reabsorption.
[C] :x: Loop of Henle: The Loop of Henle is mainly involved in concentrating the urine and reabsorbing water and ions, not glucose.
[D] :x: Collecting Duct: The collecting duct primarily regulates water and electrolyte balance; it does not significantly reabsorb glucose.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing the roles of different nephron segments:  Understanding the specific functions of each segment (PCT, DCT, Loop of Henle, Collecting Duct) is crucial.
  2.Assuming glucosuria always indicates high blood glucose:  Glucosuria can result from impaired reabsorption even with normal blood glucose levels.
 **Quick Tips**:
  1.Remember the key function of the PCT: reabsorption of glucose, amino acids, and other essential substances.
  2.Associate glucosuria with defects in the PCT's reabsorption mechanisms.

T HARITHA · Answer

The correct Option is "Proximal Convoluted Tubule (PCT)"

T HARITHA · Answer

Distal Convoluted Tubule (DCT)

T HARITHA · Answer

Loop of Henle

T HARITHA · Answer

Collecting Duct

NEET Zoology Excretory Products And Their Elimination MCQs

Select Topic

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

Question Tags

NEET Subjects

Our Bots

Company