A mutation in the gene encoding the autoimmune regulator (AIRE) protein is MOST likely to result in which immunological consequence?
Increased susceptibility to bacterial infections
Impaired isotype switching in B cells
Defective T cell development in the thymus
Development of autoimmunity against tissue-specific antigens
Related Questions
Which of the following is not an autoimmune disease ?
Vitiligo
Psoriasis
Alzheimer’s disease
Rheumatoid arthritis
Identify the wrong statement with reference to immunity
Active immunity is developed when a person's own cells produce antibodies in response to infection or vaccine
Injection of antibodies collected from patients who have recovered from a disease provides passive immunity
Certain types of leukocytes transform into memory cells in response to an antigen
Innate immunity is characterized by memory
In higher vertebrates, the immune system can distinguish self – cells and non – self. If this property is lost due to genetic abnormality and it attacks self – cells, then it leads to:
Allergic response
Graft rejection
Auto – immune disease
Active immunity
Inflammation is a characteristic of which type of immunity?
Adaptive immunity
Humoral immunity
Cell-mediated immunity
Innate immunity
Antibody is connected with
Skeletal system
Circulatory system
Immune system
Respiratory system
Which cells are responsible for producing antibodies?
T cells
Macrophages
B cells
Neutrophils
Interferon is a type of
Anti-bacterial protein
Anti-viral protein
Complex protein
Anti-clotting protein
Surgical removal of thymus of a new born shall result in the failure to produce
Basophils
Neutrophils
B-lymphocyte
T-lymphocyte
Antibodies are produced by
Leucocytes
Lymphocytes
Erythrocytes
None of these
The best HLA(Human Leucocyte Antigen) match for transplants in order of preference is
Parent>sibling>twin>unrelated donor
Sibling> twin> Parent> unrelated donor
twin> unrelated donor> parent> sibling
Twin> sibling> Parent> unrelated donor
