The Question is from neet-zoology human-welfare vaccines, and it was created by the author Mr. BALACHANDRA.N

Question

Conjugate vaccines are particularly effective against pathogens with which characteristic?

Mr. BALACHANDRA.N · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
 **Primary Concept**: Immunogenicity of polysaccharide capsules and conjugate vaccine mechanism
 **Related Topics**: Vaccine types, immune response, bacterial capsules, T-cell dependent antigens
 **Prerequisites**: Understanding of humoral and cell-mediated immunity, the role of T-helper cells in B-cell activation.
## SOLUTION PATHWAY
**Given Information**:
  The question asks about the characteristic of pathogens where conjugate vaccines are most effective.
  Options describe different pathogen characteristics.
**Method & Steps**:
 1. Understand the mechanism of conjugate vaccines.
  Reasoning: Conjugate vaccines link a poorly immunogenic polysaccharide antigen (like bacterial capsule) to a highly immunogenic protein carrier. This conjugation makes the polysaccharide more accessible to T helper cells, leading to a stronger immune response.
  Formula/Rule: None directly applicable, but understanding the mechanism is key.
 2. Analyze each option in relation to conjugate vaccine effectiveness.
  Working: Option A describes pathogens with easily immunogenic protein coats; conjugate vaccines aren't needed for such pathogens. Option B describes intracellular pathogens requiring cell-mediated immunity; conjugate vaccines primarily target extracellular polysaccharides. Option D describes pathogens with high mutation rates, which is a separate challenge unrelated to conjugate vaccine effectiveness. Option C correctly identifies polysaccharide capsules which are poorly immunogenic in young children as the target for conjugate vaccines.
  Key Point: The key is that conjugate vaccines overcome the poor immunogenicity of polysaccharide capsules by linking them to a protein carrier.
 3. Select the correct option.
  Result: Option C
  Verification: The mechanism of conjugate vaccines directly addresses the poor immunogenicity of polysaccharide capsules, particularly in young children whose immune systems haven't fully developed the ability to respond to these antigens.
 ## OPTION ANALYSIS
A :x: Protein coats that readily elicit a strong immune response are not the target of conjugate vaccines.  Conjugate vaccines are designed for antigens that are *poorly* immunogenic.
B :x: Intracellular pathogens are better targeted by cell-mediated immunity, not conjugate vaccines which primarily work with humoral immunity.
C ✓: Polysaccharide capsules are poorly immunogenic, especially in young children, making them ideal targets for conjugate vaccines which enhance their immunogenicity.
D :x: Rapid mutation rates are not directly related to the effectiveness of conjugate vaccines.  They are a separate challenge in vaccine development.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing conjugate vaccines with other vaccine types: Understanding the specific mechanism of conjugate vaccines is essential to answering this question.
  2. Focusing on the overall immunogenicity of the pathogen instead of the specific immunogenicity of the polysaccharide capsule: The question is about the specific characteristic that makes conjugate vaccines effective.
 **Quick Tips**:
  1.Remember that conjugate vaccines are specifically designed to improve the immune response to polysaccharide antigens.
  2. Associate conjugate vaccines with the poor immunogenicity of polysaccharide capsules in young children.

Mr. BALACHANDRA.N · Answer

Protein coats that readily elicit a strong immune response.

Mr. BALACHANDRA.N · Answer

Intracellular life cycle requiring cell-mediated immunity.

Mr. BALACHANDRA.N · Answer

The correct Option is "Polysaccharide capsules that are poorly immunogenic in young children."

Mr. BALACHANDRA.N · Answer

Rapid mutation rates leading to antigenic drift.

NEET Zoology Biology and Human Welfare Vaccines MCQs

Select Topic

Question Tags

NEET Subjects

Our Bots

Company