Why is Escherichia coli commonly used in the production of genetically engineered human insulin?
Easy to culture and genetically manipulate
Produces insulin naturally
Has a similar genome to humans
Is resistant to antibiotics
Related Questions
Which of the following statements is not correct ?
In man insulin is synthesised as a proinsulin
The proinsulin has an extra peptide called C-peptide
The functional insulin has A and B chains linked together by hydrogen bonds.
Genetically engineered insulin is produced in .
Which statement is INCORRECT regarding glycosidic and peptide bonds?
Both involve a condensation reaction.
Both involve a reaction between an amino group and a carboxyl group.
Both can be cleaved by hydrolysis.
Both link monomeric units to form polymers.
Read the following statements about insulin and choose the option that states all correct statements.
a. Earlier, insulin was extracted from pancreas of slaughtered cattles and pigs
b. Mature insulin do not contain polypeptide C
c. Mature insulin consists of two short polypeptides: chain A and chain B
d. During commercial production of insulin, chain A and B were produced together, extracted and combined by creating disulphide bonds
a, b and c
b, c and d
a, c and d
a, b and d
In genetically engineered insulin production, what is the role of ฮฒ-galactosidase?
Selection marker for transformed bacteria
Cleaves proinsulin into mature insulin
Promotes insulin gene transcription
Facilitates the uptake of the plasmid
What is an advantage of using genetically engineered human insulin over insulin extracted from animal sources?
Reduced risk of allergic reactions
Lower production cost
Higher insulin potency
Longer shelf life
A glycosidic bond is found in _____, while a peptide bond is characteristic of _____.
A) Steroids, Enzymes
B) Starch, Fatty acids
C) Starch, Enzymes
D) Glucose, Cholesterol
In the production of recombinant human insulin, which of the following is NOT a step involved?
Inserting the human insulin gene into E. coli
Culturing the E. coli to produce insulin chains
Extracting insulin directly from animal pancreases
Joining the A and B chains of insulin through disulfide bonds
Which of the following is now being economically produced by biotechnological procedures?
Morphine
Quinine
Insulin
Nicotine
The gene for human insulin is inserted into the bacteria's:
Plasmid
Chromosome
Ribosome
Cell wall
Insulin used for diabetes was earlier extracted from?
Liver of slaughtered cattle and pigs
Lungs of slaughtered cattle and pigs
Pancreas of slaughtered cattle and pigs
Pancreas of mice and pigs.
