In genetically engineered insulin production, what is the role of β-galactosidase?
Selection marker for transformed bacteria
Cleaves proinsulin into mature insulin
Promotes insulin gene transcription
Facilitates the uptake of the plasmid
Related Questions
Which statement incorrectly describes the role of cell division in organisms?
Meiosis is crucial for sexual reproduction.
Mitosis is primarily involved in growth and repair.
Both mitosis and meiosis involve DNA replication.
Mitosis is the process of gamete formation.
Which type of bond is crucial for maintaining the structural integrity of the two polypeptide chains in human insulin?
Hydrogen bond
Disulfide bond
Glycosidic bond
Phosphodiester bond
What is an advantage of using genetically engineered human insulin over insulin extracted from animal sources?
Reduced risk of allergic reactions
Lower production cost
Higher insulin potency
Longer shelf life
Consider the following statements about insulin
I. Human insulin is made-up of 51 amino acids arranged in two polypeptide chains
II. The two polypeptide chains are interconnected by two disulphide bridges
III. In mammals including humans, insulin is synthesized as a pro-hormone, which contains an extra stretch called the C-peptide
IV. C-peptide is not present in the mature insulin
Which of the statements given above are correct?
I, II and III
I, III and IV
II, III and IV
I, II, III and IV
Now a days insulin is extracted from.
Cattles
E. Coli
Plants
Virus
C-peptide is present in:
Mature insulin
Pro-insulin
A-peptide
B-peptide
Which of the following peptide chain is removed during the maturation of proinsulin into insulin?
A-chain (21 amino acid)
B-chain (30 amino acid)
C-chain (33 amino acid)
A and B chain
Why is Escherichia coli commonly used in the production of genetically engineered human insulin?
Easy to culture and genetically manipulate
Produces insulin naturally
Has a similar genome to humans
Is resistant to antibiotics
In the production of recombinant human insulin, which of the following is NOT a step involved?
Inserting the human insulin gene into E. coli
Culturing the E. coli to produce insulin chains
Extracting insulin directly from animal pancreases
Joining the A and B chains of insulin through disulfide bonds
Which of the following statements is not correct ?
In man insulin is synthesised as a proinsulin
The proinsulin has an extra peptide called C-peptide
The functional insulin has A and B chains linked together by hydrogen bonds.
Genetically engineered insulin is produced in .
