A 55-year-old male presents with progressive dyspnea, cough, and weight loss. A chest X-ray reveals bilateral hilar lymphadenopathy and interstitial infiltrates. Bronchoscopy with transbronchial biopsy shows non-caseating granulomas. Which of the following is the MOST likely diagnosis?
Sarcoidosis
Tuberculosis
Hypersensitivity pneumonitis
Lymphoma
Related Questions
Correct chronological order of the steps occurring during gene therapy are I. Lymphocytes are obtained from the patients II. Lymphocytes are transferred to the culture dishes III. Lymphocytes are transfected with the normal ADA genes . The transfected cell are returned to the patients The chronological order should be
I, II, III and IV
II, I, III and IV
I, III, II and IV
III, II, IV and I
Consider the following statements
I. Earlier, insulin was extracted from pancreas of slaughtered cattle and pigs which was more efficient than the genetically engineered insulin
II. PCR technique is being used for the detection of HIV in suspected AIDS patients and genetic mutations in suspected cancer patients
III. Cystic fibrosis, haemophilia, cancer, Parkinonโs etc., are treated by gene therapy
Which of the statements given above are correct?
I only
II only
I and III
II and III
For effective treatment of the disease, early diagnosis and understanding its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?
ELISA Technique
Hybridization Technique
Western Blotting Technique
Southern Blotting Technique
For effective disease management, early diagnosis and understanding the underlying mechanisms are crucial. Which molecular diagnostic technique is most valuable for early disease detection?
Polymerase Chain Reaction (PCR)
Enzyme Linked Immuno-sorbent Assay (ELISA)
Autoradiography
Southern blotting
Which type of diabetes mellitus is characterized by insulin resistance?
Type 1
Type 2
Gestational diabetes
MODY
In 1983, Eli Lilly an American company, first prepared two DNA sequences corresponding to A and B-chains of the human insulin and introduced them in the plasmids of to produce insulin chains. Chains A and B were prepared separately, extracted and combined by creating
Hydrogen bond
Disulphide bond
Covalent bond
Peptide bond
Read the following statements about agarose gel electrophoresis and choose the incorrect option.
The agarose gel used in the technique is extracted from seaweeds
The DNA fragments separate according to their size
Separated DNA fragments can be visualised after staining with ethidium bromide followed by exposure to infrared rays
DNA fragments move from cathode to anode under the influence of an electric field
Application of PCR are
I. detection of pathogens
II. diagnosis of specific mutation
III. DNA fingerprinting
Choose the correct option
I and II
I and III
II and III
I, II and III
Which molecular technique is used to detect specific RNA sequences in a sample, which can be helpful in diagnosing RNA viruses or studying gene expression?
PCR
ELISA
Southern blotting
Northern blotting