A 55-year-old male presents with progressive dyspnea, cough, and weight loss. A chest X-ray reveals bilateral hilar lymphadenopathy and interstitial infiltrates. Bronchoscopy with transbronchial biopsy shows non-caseating granulomas. Which of the following is the MOST likely diagnosis?
Sarcoidosis
Tuberculosis
Hypersensitivity pneumonitis
Lymphoma
Related Questions
Application of PCR are
I. detection of pathogens
II. diagnosis of specific mutation
III. DNA fingerprinting
Choose the correct option
I and II
I and III
II and III
I, II and III
For effective disease management, early diagnosis and understanding the underlying mechanisms are crucial. Which molecular diagnostic technique is most valuable for early disease detection?
Polymerase Chain Reaction (PCR)
Enzyme Linked Immuno-sorbent Assay (ELISA)
Autoradiography
Southern blotting
About …A… recombinant therapeutics have been approved for human use the world over. In India, …B… of these are presently being marketed Here A and B can be
300, 60
100, 80
50, 30
500, 100
Consider the following statements
I. Earlier, insulin was extracted from pancreas of slaughtered cattle and pigs which was more efficient than the genetically engineered insulin
II. PCR technique is being used for the detection of HIV in suspected AIDS patients and genetic mutations in suspected cancer patients
III. Cystic fibrosis, haemophilia, cancer, Parkinon’s etc., are treated by gene therapy
Which of the statements given above are correct?
I only
II only
I and III
II and III
Early and accurate diagnosis of genetic disorders is crucial for effective intervention. Which of the following molecular techniques is most suitable for identifying a specific gene mutation associated with a disease?
PCR and DNA Sequencing
ELISA
Autoradiography
Southern blotting
A doctor, while operating on an HIV^+ patient accidently cut himself with a scalpel. He comes to you, suspecting himself to have contacted the virus. Which test will you advise him to rule out/confirm his suspicion?
PCR
Routine urine examination
TLC
DLC
A scientist is studying a viral infection. To track the progression of the infection in a patient sample, which molecular technique would be most appropriate for quantifying the amount of viral DNA present?
PCR
Real-time PCR (qPCR)
ELISA
Southern blotting
A researcher wants to determine if a patient has a specific bacterial infection. Which of the following molecular diagnostic techniques would be LEAST suitable for this purpose?
PCR
Northern blotting
DNA probes
Culture methods
Correct chronological order of the steps occurring during gene therapy are I. Lymphocytes are obtained from the patients II. Lymphocytes are transferred to the culture dishes III. Lymphocytes are transfected with the normal ADA genes . The transfected cell are returned to the patients The chronological order should be
I, II, III and IV
II, I, III and IV
I, III, II and IV
III, II, IV and I
For effective treatment of the disease, early diagnosis and understanding its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?
ELISA Technique
Hybridization Technique
Western Blotting Technique
Southern Blotting Technique