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Histone H1 plays a crucial role in the structure of chromatin. Which of the following statements regarding its interaction and function is INCORRECT?
H1 binds to the linker DNA between nucleosomes.
H1 helps to compact chromatin structure.
H1 interacts with the core histones within the nucleosome octamer.
H1 stabilizes the interaction of DNA with the nucleosome.
A researcher isolates chromatin fibers and treats them with a nuclease that specifically cleaves linker DNA. Following this treatment, what would be the approximate size distribution of the DNA fragments observed?
Approximately 200 bp
Approximately 1000 bp
Approximately 50 bp
A wide range of sizes from 200 bp to several thousand bp
In an experiment, a researcher selectively removes histone H4 from chromatin. Which of the following is the MOST likely immediate consequence?
Increased condensation of the chromatin fiber.
Enhanced binding of RNA polymerase to promoter regions.
Specific activation of a subset of genes.
Significant destabilization of the nucleosome core and loss of DNA wrapping.
Which of the following is the basic repeating unit of chromatin?
Gene
Chromosome
Centromere
Nucleosome
The structure formed by DNA wrapped around histone proteins is called:
Chromosome
Chromatid
Chromatin
Centromere
In eukaryotes, the fundamental repeating unit of chromatin is called a:
Solenoid
Chromatid
Centromere
Nucleosome
Approximately how many base pairs of DNA are wrapped around a single nucleosome core?
200
50
146
250
The 'beads-on-a-string' appearance of chromatin is due to:
Supercoiled DNA
Condensed chromosomes
Looped chromatin fibers
Nucleosomes connected by linker DNA
Which of these processes is directly influenced by the level of chromatin compaction?
DNA replication
RNA processing
Gene expression
Protein translation
