The Question is from neet-botany , and it was created by the author K SURESH KUMAR

Question

Ex vivo gene therapy involves:

K SURESH KUMAR · Accepted Answer

## CORE INFORMATION
✓ **Answer**: [B]
## CONCEPT FRAMEWORK
	**Primary Concept**: Ex vivo gene therapy
	**Related Topics**: Gene therapy, Cell modification, Genetic engineering
	**Prerequisites**: Understanding of gene therapy methodologies
## SOLUTION PATHWAY
**Given Information**:
		- Ex vivo gene therapy is a technique used to treat genetic disorders.
		- Involves manipulation of cells outside the body.
**Method & Steps**:
	1. Identify the method of gene introduction.
		Reasoning: Ex vivo means that the cells are modified before being introduced into the body.
		Formula/Rule: N/A
	2. Determine the procedure for cell modification.
		Working: Cells are extracted, modified in a laboratory setting, and then returned to the patient.
		Key Point: This contrasts with in vivo methods where the gene is introduced directly into the body.
	3. Conclude on the nature of the therapy.
		Result: The correct description of ex vivo gene therapy is modifying cells outside the body.
		Verification: This aligns with the definition of ex vivo.
## OPTION ANALYSIS
[A] :x: Direct injection does not define ex vivo therapy as it refers to in vivo methods.
[B] ✓: Correctly describes the process of ex vivo gene therapy.
[C] :x: This defines in vivo therapy, not ex vivo.
[D] :x: Modifying germline cells is not typical in ex vivo therapy; it usually focuses on somatic cells.
## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing ex vivo with in vivo: Remember that ex vivo involves outside manipulation.
		2. Misunderstanding the target cells: Ex vivo typically involves somatic cells, not germline modifications.
	**Quick Tips**:
		1. Associate 'ex vivo' with 'outside' to help remember the process.
		2. Recall that 'in vivo' means 'within the living organism' for distinction.

K SURESH KUMAR · Answer

Directly injecting the therapeutic gene into the patient

K SURESH KUMAR · Answer

The correct Option is "Modifying cells outside the body and then reintroducing them"

K SURESH KUMAR · Answer

Using a viral vector to deliver the gene in vivo

K SURESH KUMAR · Answer

Modifying germline cells to correct genetic defects

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