The Question is from neet-zoology excretory-products-and-their-elimination roles-of-other-organs-in-excretion, and it was created by the author K SUNKANNA

Question

Individuals with chronic kidney disease often experience a decrease in erythropoietin production.  Which of the following consequences is MOST directly related to this reduced erythropoietin level?

K SUNKANNA · Accepted Answer

## CORE INFORMATION
✓ **Answer**: B
## CONCEPT FRAMEWORK
 **Primary Concept**: Erythropoietin's role in red blood cell production
 **Related Topics**: Chronic kidney disease, anemia, hematocrit, oxygen transport
 **Prerequisites**: Basic understanding of blood cell formation and oxygen transport.
## SOLUTION PATHWAY
**Given Information**:
  Individuals with chronic kidney disease have reduced erythropoietin production.
  Options: Increased blood pressure, decreased oxygen-carrying capacity, elevated blood calcium, impaired glucose metabolism.
**Method & Steps**:
 1. Understand Erythropoietin's function:
  Reasoning: Erythropoietin (EPO) is a hormone primarily produced by the kidneys. Its crucial function is to stimulate the bone marrow to produce red blood cells (erythrocytes).
  Formula/Rule:  No specific formula is needed here; it's a conceptual understanding.
 2. Analyze the consequences of reduced EPO:
  Working:  If EPO production is decreased, the bone marrow will produce fewer red blood cells. This directly leads to a lower number of erythrocytes in the blood, resulting in a decreased capacity to carry oxygen.
  Key Point:  The other options are consequences of CKD but are not the *most direct* result of reduced EPO.  For example, impaired glucose metabolism is a general complication of CKD, not directly linked to EPO deficiency.
 3. Identify the most direct consequence:
  Result: Decreased oxygen-carrying capacity of the blood is the most direct and immediate consequence of reduced erythropoietin levels.
  Verification: The logical chain is clear: less EPO → fewer red blood cells → reduced oxygen-carrying capacity.
 ## OPTION ANALYSIS
A :x: Increased blood pressure is a potential consequence of CKD but not directly caused by reduced EPO.
B ✓: Decreased oxygen-carrying capacity of the blood is the direct result of fewer red blood cells due to reduced EPO stimulation of their production.
C :x: Elevated blood calcium levels are related to CKD but are not a direct consequence of reduced EPO.
D :x: Impaired glucose metabolism is another complication of CKD, unrelated to EPO levels.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing the effects of CKD with the direct effect of reduced EPO:  CKD causes many problems, but the question focuses specifically on the effect of reduced EPO.
  2.Failing to understand the fundamental role of EPO in erythropoiesis (red blood cell production):  This is key to solving the question.
 **Quick Tips**:
  1.Remember that EPO is the key hormone for red blood cell production.
  2.Focus on the direct causal link between EPO levels and the consequences listed in the options.

K SUNKANNA · Answer

Increased blood pressure

K SUNKANNA · Answer

The correct Option is "Decreased oxygen-carrying capacity of the blood"

K SUNKANNA · Answer

Elevated blood calcium levels

K SUNKANNA · Answer

Impaired glucose metabolism

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