A patient presents with a tumor that shows evidence of loss of heterozygosity (LOH) at a specific locus. Which of the following is the MOST likely explanation for this observation and its significance in cancer development?
Duplication of the mutated allele of an oncogene; Inhibits tumor formation.
Deletion of the normal allele of a tumor suppressor gene; Promotes tumor formation.
Translocation involving a proto-oncogene; Has no effect on tumor formation.
Inversion within a tumor suppressor gene; Suppresses tumor formation.
Related Questions
Cells obtained from cancerous tumours are known as
Normal cells
Tumor cells
Stem cells
Blood cells
Proliferation of cancer cells is not limited because of
Loss of cell cycle control and evasion of apoptosis
Increased cellular differentiation and specialization
Enhanced contact inhibition and growth factor dependence
Limited access to nutrients and oxygen
Cancer cells are more easily damaged by radiation than normal cells because they are
Starved of mutation
Undergoing rapid division
Different in structure
Non-dividing
Hela cells used in cell biology are
Cancerous cells grown in cancer research laboratory
Cervical cancer cell derivatives
Both (a) and (b)
None of the above
Which one of the following is not the property of cancerous cells?
They do not require extracellular growth factors
They do not remain confined in the area of formation
They show contact inhibition
They divide in an uncontrolled manner
