A patient presents with a tumor that shows evidence of loss of heterozygosity (LOH) at a specific locus. Which of the following is the MOST likely explanation for this observation and its significance in cancer development?
Duplication of the mutated allele of an oncogene; Inhibits tumor formation.
Deletion of the normal allele of a tumor suppressor gene; Promotes tumor formation.
Translocation involving a proto-oncogene; Has no effect on tumor formation.
Inversion within a tumor suppressor gene; Suppresses tumor formation.
Related Questions
Cancerous cells spread through
Lymph
Blood
Secondary growths of malignant tumour
All of the above
