Which of these is NOT an advantage of using genetically engineered insulin?
Higher cost compared to animal-derived insulin
Reduced risk of allergic reactions
Larger and more reliable supply
Higher purity
Related Questions
A scientist aims to modify the human insulin gene to increase its binding affinity to the insulin receptor. Which amino acid substitution within the insulin A-chain is MOST likely to achieve this, considering its role in receptor interaction?
A. Valine at A3 to Leucine
B. Glycine at A1 to Glutamic acid
C. Isoleucine at A2 to Valine
D. Glutamine at A5 to Asparagine
The production of human insulin in bacteria involves the insertion of the human gene for insulin into a bacterial plasmid. This plasmid then acts as a:
Vector
Promoter
Operator
Repressor
C – Peptide of human insulin is
A part of mature insulin molecule
Responsible for formation of disulphide bridges
Removed during maturation of pro-insulin to insulin
Responsible for its biological activity
Mature insulin consists of?
Two long polypeptide chains
Two long polynucleotide chains
Two short polypeptide chains
Two short polynucleotide chains
Which one of the following is the most suitable, medium for culture of Drosophila melanogaster?
Moist bread
Agar agar
Ripe banana
Cow dung
Why is Escherichia coli commonly used in the production of genetically engineered human insulin?
Easy to culture and genetically manipulate
Produces insulin naturally
Has a similar genome to humans
Is resistant to antibiotics
Which of the following statements is not correct ?
In man insulin is synthesised as a proinsulin
The proinsulin has an extra peptide called C-peptide
The functional insulin has A and B chains linked together by hydrogen bonds.
Genetically engineered insulin is produced in .
The term ‘Humulin’ is used for
Hydrolytic enzyme
Powerful antibiotic
Human insulin
Human Antibodies
What is the role of C-peptide in the context of insulin production?
Forms disulfide bonds between A and B chains
Connects the A and B chains in proinsulin
Is part of the mature insulin molecule
Facilitates the insertion of the insulin gene into bacteria
What is the demerit of using bovine insulin (from cow) and porcine insulin (from pig) in diabetic patients?
It leads to hypercalcemia
It is expensive
It may cause allergic reactions
It may lead to mutations in human genome
