Why is genetically engineered insulin preferred over insulin derived from animal sources?
It reduces the risk of allergic reactions and is more readily available.
It is less effective than animal insulin.
It is more expensive to produce.
It is not as pure as animal insulin.
Related Questions
In genetically engineered insulin production, what is the role of ฮฒ-galactosidase?
Selection marker for transformed bacteria
Cleaves proinsulin into mature insulin
Promotes insulin gene transcription
Facilitates the uptake of the plasmid
What enzyme is used to 'cut' and 'paste' DNA in genetic engineering?
Restriction enzymes and ligase
DNA polymerase
RNA polymerase
Reverse transcriptase
Insulin used for diabetes was earlier extracted from?
Liver of slaughtered cattle and pigs
Lungs of slaughtered cattle and pigs
Pancreas of slaughtered cattle and pigs
Pancreas of mice and pigs.
Assertion: Disulfide bonds are important for the stability of human insulin.
Reason: These bonds link the two polypeptide chains of insulin together.
Choose the correct option:
Both Assertion and Reason are true, and Reason is the correct explanation for Assertion.
Both Assertion and Reason are true, but Reason is not the correct explanation for Assertion.
Assertion is true, but Reason is false.
Assertion is false, but Reason is true.
Consider the following statements about insulin
I. Human insulin is made-up of 51 amino acids arranged in two polypeptide chains
II. The two polypeptide chains are interconnected by two disulphide bridges
III. In mammals including humans, insulin is synthesized as a pro-hormone, which contains an extra stretch called the C-peptide
IV. C-peptide is not present in the mature insulin
Which of the statements given above are correct?
I, II and III
I, III and IV
II, III and IV
I, II, III and IV
C โ Peptide of human insulin is
A part of mature insulin molecule
Responsible for formation of disulphide bridges
Removed during maturation of pro-insulin to insulin
Responsible for its biological activity
Which of the following statements is incorrect regarding insulin produced by rDNA technology?
It is readily available.
It is identical to human insulin.
It avoids ethical concerns associated with animal-derived insulin.
It always contains C-peptide.
The two polypeptide chains of human insulin are interconnected by:
Hydrogen bonds
Disulfide bridges
Peptide bonds
Ionic bonds
A researcher is attempting to express human proinsulin in a eukaryotic expression system like yeast. Compared to bacterial systems, what distinct advantage does this offer concerning post-translational modifications?
A. Yeast can directly cleave proinsulin into active insulin without the need for enzymatic treatment
B. Yeast can perform glycosylation, which may enhance insulin stability or activity
C. Yeast prevents the formation of inclusion bodies, simplifying purification
D. Yeast systems eliminate the risk of endotoxin contamination
Mature insulin consists of?
Two long polypeptide chains
Two long polynucleotide chains
Two short polypeptide chains
Two short polynucleotide chains
