The Question is from neet-botany plant-growth-and-development , and it was created by the author D VINOD

Question

A mutation affects the function of the Hox genes in a developing Drosophila embryo. Which of the following is the MOST likely consequence?

D VINOD · Accepted Answer

## CORE INFORMATION
✓ **Answer**: [C]
## CONCEPT FRAMEWORK
	**Primary Concept**: Hox genes and their role in development
	**Related Topics**: Gene regulation, embryonic development, homeotic mutations
	**Prerequisites**: Understanding of genetics and developmental biology
## SOLUTION PATHWAY
**Given Information**:
		- Mutation in Hox genes
		- Hox genes are crucial for determining body plan during embryonic development
**Method & Steps**:
	1. Identify the role of Hox genes.
		Reasoning: Hox genes are responsible for the anterior-posterior axis specification and segment identity in organisms.
		Formula/Rule: Hox gene expression patterns dictate segmental identity.
	2. Analyze the consequences of mutations in these genes.
		Working: Mutations in Hox genes often lead to homeotic transformations, where one body segment develops characteristics of another segment.
		Key Point: This is a well-documented phenomenon in various organisms including Drosophila.
	3. Conclude the most likely consequence of such a mutation.
		Result: Homeotic transformations, leading to segments developing with characteristics of other segments.
		Verification: This matches known outcomes of Hox gene mutations.
## OPTION ANALYSIS
[A] :x: Premature termination of embryonic development: This is not a typical consequence of Hox gene mutations; they primarily affect segment identity.
[B] :x: Failure of gastrulation: Hox genes are not primarily involved in the process of gastrulation.
[C] ✓: Homeotic transformations, leading to segments developing with characteristics of other segments: Correct, as Hox mutations lead to mis-specification of segments.
[D] :x: Lack of differentiation of germ layers: This is unrelated to the function of Hox genes, which act later in development.
## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing the roles of Hox genes with early developmental processes: Understand that Hox genes function later in development.
		2. Misinterpreting the effects of mutations in developmental genes: Focus on segment identity and transformations.
	**Quick Tips**:
		1. Remember that Hox genes are 'homeotic' genes; they determine 'what' body part is formed where.
		2. Recall that mutations in Hox genes can lead to dramatic changes in morphology, well illustrated in Drosophila studies.

D VINOD · Answer

Premature termination of embryonic development.

D VINOD · Answer

Failure of gastrulation.

D VINOD · Answer

The correct Option is "Homeotic transformations, leading to segments developing with characteristics of other segments."

D VINOD · Answer

Lack of differentiation of germ layers.

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