The Question is from neet-botany , and it was created by the author K SURESH KUMAR

Question

A mutation in an aquaporin gene results in a non-functional protein. Which of the following cellular processes would be MOST directly affected?

K SURESH KUMAR · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
 **Primary Concept**: Aquaporin function and water transport
 **Related Topics**: Membrane transport, kidney physiology, osmosis
 **Prerequisites**: Understanding of protein function, membrane structure, and water transport mechanisms.
## SOLUTION PATHWAY
**Given Information**:
A mutation renders aquaporin proteins non-functional.
**Method & Steps**:
1. Identify the function of aquaporins.
  Reasoning: Aquaporins are channel proteins that facilitate the rapid movement of water across cell membranes.
  Formula/Rule:  No specific formula is needed here; this is a conceptual question.
2. Consider the options and determine which process relies most directly on aquaporin function.
  Working: 
	* Option A (Glucose uptake): Glucose transport uses glucose transporters, not aquaporins.
	* Option B (Sodium transport): Sodium transport involves ion channels and pumps, not aquaporins.
	* Option C (Water reabsorption in kidneys): The kidneys reabsorb a large volume of water through aquaporins located in the collecting ducts.
	* Option D (Calcium storage): Calcium storage involves specialized proteins in the sarcoplasmic reticulum, not aquaporins.
  Key Point:  Aquaporins are highly specific for water transport.
3. Determine the most directly affected process.
  Result: Water reabsorption in the kidneys is the process most directly affected by non-functional aquaporins.
  Verification:  The other options involve different transport mechanisms, making them less directly reliant on aquaporins.
 ## OPTION ANALYSIS
A :x: Glucose uptake is mediated by glucose transporters, not aquaporins.
B :x: Sodium transport utilizes ion channels and pumps, not aquaporins.
C ✓: Water reabsorption in the kidneys is heavily dependent on the function of aquaporins in the collecting duct.
D :x: Calcium storage in the sarcoplasmic reticulum is not directly related to aquaporin function.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing aquaporins with other membrane transport proteins: Remember aquaporins are specific for water.
  2.Focusing on general water movement instead of the specific role of aquaporins: Aquaporins are crucial for *rapid* water movement.
 **Quick Tips**:
  1.Memorize the function of aquaporins as water channels.
  2.Associate aquaporins with water balance and kidney function.

K SURESH KUMAR · Answer

Glucose uptake by muscle cells

K SURESH KUMAR · Answer

Sodium transport across nerve cell membranes

K SURESH KUMAR · Answer

The correct Option is "Water reabsorption in the kidneys"

K SURESH KUMAR · Answer

Calcium storage in the sarcoplasmic reticulum

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