The Question is from neet-botany , and it was created by the author K SURESH KUMAR

Question

Which of the following events does not occur in rough endoplasmic reticulum ?

K SURESH KUMAR · Accepted Answer

## CORE INFORMATION
✓ **Answer**: A
## CONCEPT FRAMEWORK
**Primary Concept**: Functions of the Rough Endoplasmic Reticulum (RER)
**Related Topics**: Cellular organelles, Protein synthesis and processing, Lipid synthesis
**Prerequisites**: Basic knowledge of cell biology, understanding of organelle functions
## SOLUTION PATHWAY
**Given Information**:
* Question asks for the process that DOES NOT occur in the RER.
* Options include phospholipid synthesis, protein folding, signal peptide cleavage, and protein glycosylation.
**Method & Steps**:
1. **Recall the primary functions of the RER:** The RER is primarily involved in protein synthesis and processing, including folding, modification, and trafficking of proteins destined for the cell membrane, secretion, or other organelles.
2. **Evaluate each option based on RER function:**
    * A. Phospholipid synthesis is a function of the Smooth Endoplasmic Reticulum (SER), not the RER.
    * B. Protein folding is a core function of the RER, facilitated by chaperone proteins.
    * C. Cleavage of the signal peptide is part of protein processing that occurs in the RER lumen.
    * D. Protein glycosylation is another key modification process performed in the RER.
3. **Identify the exception:** Option A is the only function that is not associated with the RER.
**Result**: Option A is the correct answer
**Verification**: All options except A are known functions of the RER
## OPTION ANALYSIS
[A] ✓: Phospholipid synthesis occurs primarily in the smooth endoplasmic reticulum, not the rough endoplasmic reticulum.
[B] :x: Protein folding is a major function of the rough endoplasmic reticulum.
[C] :x: Signal peptide cleavage occurs in the rough endoplasmic reticulum during protein translocation.
[D] :x: Protein glycosylation is another modification that occurs in the rough endoplasmic reticulum.
## LEARNING AIDS
**Common Mistakes**:
1. Confusing RER and SER functions: RER is mainly for protein processing, while SER is for lipid synthesis, detoxification, and calcium storage.
2. Forgetting the specific steps of protein processing: RER is involved in folding, signal peptide cleavage, and glycosylation.
**Quick Tips**:
1. Remember that the 'rough' in RER comes from the ribosomes attached to its surface, which are involved in protein synthesis.
2. Think 'proteins' for RER and 'lipids' for SER as a simple way to remember their main functions.

K SURESH KUMAR · Answer

The correct Option is "Phospholipid synthesis "

K SURESH KUMAR · Answer

Protein folding

K SURESH KUMAR · Answer

Cleavage of signal peptide

K SURESH KUMAR · Answer

Protein glycosylation

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