The Question is from neet-botany , and it was created by the author NISHANTH

Question

Which organelle is responsible for the detoxification of drugs and poisons, especially in liver cells?

NISHANTH · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
 **Primary Concept**: Cell Organelle Functions
 **Related Topics**: Liver function, detoxification processes, smooth ER enzymes
 **Prerequisites**: Basic understanding of cell organelles and their roles.
## SOLUTION PATHWAY
**Given Information**:
  The question asks about the organelle primarily responsible for detoxification, particularly in liver cells.
  Important conditions: The focus is on detoxification of drugs and poisons.
**Method & Steps**:
 1. Identify organelles involved in detoxification.
  Reasoning: Several organelles contribute to cellular detoxification, but one stands out for its role in processing toxins.
  Formula/Rule: N/A
 2. Analyze the roles of each option.
  Working: 
            * Lysosomes: Primarily involved in waste breakdown and recycling.
            * Rough Endoplasmic Reticulum (RER):  Synthesizes proteins.
            * Smooth Endoplasmic Reticulum (SER): Synthesizes lipids, metabolizes carbohydrates, and detoxifies drugs and poisons.  It contains enzymes like cytochrome P450 that are crucial for this process.
            * Peroxisomes: Involved in breaking down fatty acids and other molecules, producing hydrogen peroxide as a byproduct, which they then break down.
  Key Point: The smooth ER is particularly abundant in liver cells, reflecting its critical role in hepatic detoxification.
 3. Determine the most appropriate organelle.
  Result: Smooth Endoplasmic Reticulum (SER)
  Verification: The SER's role in detoxification is well-established in biology and especially relevant in liver cells.
 ## OPTION ANALYSIS
A :x: Lysosomes are responsible for intracellular digestion, not primarily detoxification of exogenous compounds.
B :x: The rough ER is involved in protein synthesis, not directly in detoxification of drugs and poisons.
C ✓: The smooth ER is the primary site for detoxification of drugs and poisons, especially in liver cells. It contains enzymes like cytochrome P450 that catalyze reactions leading to the inactivation of many toxins.
D :x: Peroxisomes primarily participate in the breakdown of fatty acids and other metabolites, not the detoxification of drugs and poisons to the same extent as the SER.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing the roles of the smooth and rough ER: Remember that the smooth ER lacks ribosomes and is involved in lipid synthesis and detoxification, while the rough ER has ribosomes and is involved in protein synthesis.
  2.Overlooking the significance of liver cells: The question specifically mentions liver cells, highlighting the abundance of smooth ER in these cells and their central role in detoxification.
 **Quick Tips**:
  1.Associate “smooth ER” with “lipid synthesis” and “detoxification”.
  2.Remember the liver's role in filtering blood and detoxifying substances.

NISHANTH · Answer

Lysosomes

NISHANTH · Answer

Rough Endoplasmic Reticulum

NISHANTH · Answer

The correct Option is "Smooth Endoplasmic Reticulum"

NISHANTH · Answer

Peroxisomes

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