The Question is from neet-zoology body-fluids-and-circulation , and it was created by the author Mr. BALACHANDRA.N

Question

A person with blood group A receives a transfusion of blood group B. Which of the following is the MOST IMMEDIATE consequence due to the preformed antibodies in the recipient's plasma?

Mr. BALACHANDRA.N · Accepted Answer

## CORE INFORMATION
✓ **Answer**: B
## CONCEPT FRAMEWORK
	**Primary Concept**: Blood Groups and Transfusion Reactions
	**Related Topics**: Antibodies, Antigens, Agglutination, Immune System
	**Prerequisites**: Understanding of ABO blood group system and antigen-antibody interactions.
## SOLUTION PATHWAY
**Given Information**:
	Blood group A recipient receives blood group B transfusion.
**Method & Steps**:
	1. **Identify preformed antibodies**: A person with blood group A has preformed anti-B antibodies in their plasma.
		Reasoning: Individuals naturally develop antibodies against the ABO antigens they lack.
	2. **Antigen-antibody interaction**: When blood group B is introduced, the anti-B antibodies in the recipient's plasma immediately recognize the B antigens on the donor red blood cells.
		Working: Anti-B antibodies bind to B antigens.
		Key Point: This binding is highly specific.
	3. **Agglutination**: The binding of antibodies to antigens causes the donor red blood cells to clump together, a process called agglutination.
		Result: Agglutination of donor red blood cells.
		Verification: This is the immediate and most significant consequence of incompatible blood transfusion.
## OPTION ANALYSIS
[A] :x: Production of anti-A antibodies: The recipient already has A antigens and therefore would not produce anti-A antibodies.  The transfusion introduces B antigens, so if any new antibody production were to occur (which is not the immediate consequence), it would be anti-B (which they already have). 
[B] ✓: Agglutination of the donor red blood cells: This is the correct answer as explained above. The preformed anti-B antibodies in the recipient's plasma will immediately bind to the B antigens on the donor red blood cells, leading to agglutination.
[C] :x: Production of anti-Rh antibodies:  Rh incompatibility can cause problems, but the question specifically asks about the MOST IMMEDIATE consequence due to *preformed* antibodies.  Anti-Rh antibodies are not preformed in the same way as ABO antibodies; they develop after exposure to Rh+ blood. 
[D] :x: No reaction: This is incorrect. A transfusion reaction is expected due to the ABO incompatibility.
## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing donor and recipient blood groups: Always clarify which blood group belongs to the donor and the recipient to avoid misinterpreting the reaction.
		2. Overlooking preformed antibodies: Remember that individuals have preformed antibodies against the ABO antigens they lack. This is the key to understanding immediate transfusion reactions.
	**Quick Tips**:
		1. Remember the saying 'Type O is the universal donor, Type AB is the universal recipient'.
		2. Visualize the antigen-antibody interaction as a lock and key mechanism to understand the specificity of the reaction.

Mr. BALACHANDRA.N · Answer

Production of anti-A antibodies

Mr. BALACHANDRA.N · Answer

The correct Option is "Agglutination of the donor red blood cells"

Mr. BALACHANDRA.N · Answer

Production of anti-Rh antibodies

Mr. BALACHANDRA.N · Answer

No reaction

NEET Zoology Body Fluids And Circulation MCQs

Select Topic

Question Tags

Question Tags

Question Tags

Question Tags

NEET Subjects

Our Bots

Company