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In individuals with blood type AB, which of the following BEST describes the interaction between their blood serum and erythrocytes from a type O individual?
No agglutination occurs
Agglutination occurs due to anti-A antibodies
Agglutination occurs due to anti-B antibodies
Agglutination occurs due to both anti-A and anti-B antibodies
A rare genetic mutation leads to the production of erythrocytes with significantly reduced surface area. What would be the MOST likely physiological consequence of this mutation?
Increased blood viscosity
Reduced oxygen-carrying capacity
Enhanced carbon dioxide transport
Elevated red blood cell count
A patient suffering from severe burns experiences extensive plasma loss. Which of the following blood components would be MOST crucial to administer immediately to stabilize their circulatory volume?
Packed red blood cells
Platelet concentrate
Plasma expanders like dextran
Whole blood
Which specific component of the hemoglobin molecule undergoes reversible binding with oxygen?
Globin chains
Iron within the heme group
Protoporphyrin ring
Histidine residues
A patient presents with chronic fatigue, pallor, and shortness of breath. Blood tests reveal microcytic, hypochromic red blood cells. Further investigation shows a defect in iron absorption in the intestines. Which of the following conditions is MOST likely responsible for these findings?
Pernicious anemia
Sickle cell anemia
Iron-deficiency anemia
Thalassemia
A person with blood group A receives a transfusion of blood group B. Which of the following is the MOST IMMEDIATE consequence due to the preformed antibodies in the recipient's plasma?
Production of anti-A antibodies
Agglutination of the donor red blood cells
Production of anti-Rh antibodies
No reaction
A pregnant woman with blood group O negative and her fetus is Rh positive. During her second pregnancy, which specific antibody crosses the placenta and causes erythroblastosis fetalis?
Anti-A IgM
Anti-B IgG
Anti-D IgG
Anti-O IgM
In a paternity dispute, the mother has blood group AB and the child has blood group O. Which of the following blood groups COULD NOT be the father's?
A
B
AB
O
Which rare blood group phenotype arises from the absence of H substance, preventing the expression of A and B antigens even with the presence of or alleles?
Para-Bombay phenotype
Bombay phenotype
Rh null phenotype
Secretor phenotype
A patient needs a blood transfusion. Their blood sample agglutinates with anti-A and anti-B sera but not with anti-D serum. What is the SAFEST blood group for transfusion to this patient, considering both ABO and Rh factors?
A positive
B negative
AB negative
O negative