The Question is from neet-zoology chemical-coordincation-and-integration the-pituitary-gland, and it was created by the author A SUBRAMANYAM

Question

Which of the following is NOT a direct effect of Growth Hormone (GH)?

A SUBRAMANYAM · Accepted Answer

## CORE INFORMATION
✓ **Answer**: C
## CONCEPT FRAMEWORK
 **Primary Concept**: Effects of Growth Hormone (GH)
 **Related Topics**: Endocrine system, protein synthesis, lipolysis, bone growth, insulin-like growth factor 1 (IGF-1)
 **Prerequisites**: Basic understanding of hormone function and metabolic processes.
## SOLUTION PATHWAY
**Given Information**:
  The question asks to identify the effect that is NOT a direct consequence of GH.
  Options: Increased protein synthesis, increased lipolysis, increased calcium absorption in the intestines, stimulation of IGF-1 production.
**Method & Steps**:
 1. Analyze each option's relationship with GH.
  Reasoning: Growth hormone directly influences various metabolic processes. We need to determine which effect is not a direct consequence of GH's action.
  Formula/Rule:  There's no specific formula, but understanding the mechanisms of GH action is crucial.
 2. Evaluate each option based on the known effects of GH.
  Working: 
        * **Increased protein synthesis:** GH stimulates protein synthesis directly by increasing amino acid uptake into cells and promoting ribosome activity.
        * **Increased lipolysis:** GH promotes the breakdown of fats (lipolysis) for energy, directly influencing fat metabolism.
        * **Increased calcium absorption in the intestines:** While GH indirectly influences bone growth which requires calcium, the direct effect of GH on calcium absorption is minimal.  It primarily acts through IGF-1, which has a more significant role in calcium metabolism.
        * **Stimulation of IGF-1 production:** GH's primary mechanism of action is by stimulating the liver (and other tissues) to produce IGF-1, which then mediates many of GH's growth-promoting effects.
 3. Identify the option that is NOT a direct effect.
  Result: Increased calcium absorption in the intestines (option C) is not a direct effect of GH. It is largely an indirect effect mediated by IGF-1.
  Verification:  Review the known mechanisms of GH action and its relationship with IGF-1 and calcium metabolism confirms that option C is the correct answer.
 ## OPTION ANALYSIS
A ✓: Increased protein synthesis is a direct effect of GH.
B :x: Increased lipolysis is a direct effect of GH.
C :x: Increased calcium absorption in the intestines is NOT a direct effect of GH; it's primarily mediated by IGF-1.
D :x: Stimulation of IGF-1 production is a direct effect of GH.
 ## LEARNING AIDS
 **Common Mistakes**:
  1.Confusing direct and indirect effects of hormones: Understand the difference between the primary action of a hormone and the secondary effects mediated by other factors.
  2.Overlooking the role of intermediary molecules like IGF-1:  Recognize that many hormone effects are not direct but mediated through secondary messengers or other hormones.
 **Quick Tips**:
  1.Focus on the primary actions of GH: Remember that GH primarily affects protein synthesis, lipolysis, and IGF-1 production.
  2.Think of IGF-1 as a mediator:  Many of the growth-related effects attributed to GH are actually mediated by IGF-1.

A SUBRAMANYAM · Answer

Increased protein synthesis

A SUBRAMANYAM · Answer

Increased lipolysis

A SUBRAMANYAM · Answer

The correct Option is "Increased calcium absorption in the intestines"

A SUBRAMANYAM · Answer

Stimulation of IGF-1 production

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