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NEET Questions / Zoology / Excretory Products And Their Elimination
A rare genetic disorder leads to impaired urea transport across cell membranes within the nephron. Which region's function would be MOST directly compromised, leading to a significant disruption in the establishment of the medullary concentration gradient?
Proximal Convoluted Tubule
Distal Convoluted Tubule
Thick Ascending Limb of the Loop of Henle
Collecting Duct
A rare genetic disorder impairs the function of the Na+-K+-2Cl- cotransporter in the thick ascending limb of the loop of Henle. Which of the following would be the MOST direct consequence of this defect?
Increased potassium excretion
Metabolic alkalosis
Impaired urine concentrating ability
Increased glucose reabsorption
Which of the following combinations of factors would MOST significantly impair the kidney's ability to produce concentrated urine?
High ADH levels and increased water permeability of the collecting duct
Low ADH levels and increased urea recycling in the medulla
High ADH levels and impaired Na+ reabsorption in the thick ascending limb
Low ADH levels and impaired Na+ reabsorption in the thick ascending limb
Which process plays a crucial role in concentrating the filtrate in the Loop of Henle?
Active transport
Passive transport
Countercurrent mechanism
Filtration
What is the primary function of the vasa recta in the kidney?
Filtering blood
Maintaining the medullary concentration gradient
Secreting hormones
Storing urine
The descending limb of the loop of Henle is permeable to which substance, contributing to the concentration of the filtrate?
Sodium ions
Potassium ions
Urea
Water
The countercurrent mechanism in the Loop of Henle is primarily responsible for:
Filtering large proteins
Secreting potassium ions
Maintaining a concentration gradient in the medullary interstitium
Reabsorbing bicarbonate ions
The counter current mechanism operates in nephron
In ascending and descending limb of vasa recta
In ascending limb of Henle’s loop
In descending limb of Henle’s loop
Between the loop of Henle and vasa recta
The counter current mechanism operates in nephron
In ascending and descending limb of vasa recta
In ascending limb of Henle’s loop
In descending limb of Henle’s loop
Between the loop of Henle and vasa recta
Counter current mechanism helps to maintain a concentration gradient. This gradient help in
Easy passage of water from medulla to collecting tubule and thereby concentrating urine
Easy passage of water from collecting tubule to interstitial fluid and thereby concentrating urine
Easy passage of water from medullary interstitial fluid to collecting tubule and thereby diluting urine
Inhibition of passage of water between the collecting tubule and medulla and so isotonic urine is formed
