The Question is from neet-zoology , and it was created by the author A SUBRAMANYAM

Question

Identify the correct statement on ‘inhibin’:

A SUBRAMANYAM · Accepted Answer

## CORE INFORMATION
✓ **Answer**: B
## CONCEPT FRAMEWORK
	**Primary Concept**: Endocrine Regulation of Reproduction
	**Related Topics**: Hormone Feedback Mechanisms, Gonadal Function, Pituitary Gland
	**Prerequisites**: Basic understanding of the hypothalamic-pituitary-gonadal axis.
## SOLUTION PATHWAY
**Given Information**:
	The question asks about the source and function of inhibin.
**Method & Steps**:
	1. **Recall the role of inhibin**: Inhibin is a hormone that plays a crucial role in regulating the reproductive system, specifically by providing negative feedback to the pituitary gland.
		Reasoning: Inhibin primarily inhibits the secretion of follicle-stimulating hormone (FSH).
	2. **Identify the source of inhibin**:
		Working: In males, inhibin is produced by the Sertoli cells in the testes. In females, it is produced by the granulosa cells in the ovaries.
		Key Point:  Leydig cells in males produce testosterone, and the corpus luteum produces progesterone.  The pituitary gland produces FSH and LH, which are regulated by inhibin, not the other way around.
	3. **Match the source and function with the options**:
		Result: Option B correctly states that inhibin is secreted by Sertoli cells in males and granulosa cells in females and inhibits FSH secretion.
		Verification: This aligns with the established understanding of inhibin's role in regulating FSH secretion.
## OPTION ANALYSIS
[A] :x: Inhibin is not secreted by Leydig cells (which secrete testosterone).  While inhibin does indirectly affect LH levels by reducing FSH, its primary inhibitory action is on FSH, not LH.
[B] ✓: This option correctly identifies the source (Sertoli and granulosa cells) and primary function (inhibition of FSH secretion) of inhibin. 
[C] :x: Inhibin is not secreted by the pituitary gland.  The pituitary gland secretes FSH and LH, and inhibin provides negative feedback to regulate their secretion, primarily FSH.
[D] :x: Inhibin is not secreted by the corpus luteum (which secretes progesterone). While the corpus luteum plays a role in the reproductive cycle, it is not involved in inhibin production.
## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing the roles of inhibin and activin: Activin, also produced by gonadal cells, stimulates FSH secretion, contrasting with inhibin's inhibitory role.
		2. Misattributing the source of inhibin: Remember that Sertoli and granulosa cells produce inhibin, while Leydig cells produce testosterone and the corpus luteum produces progesterone.
	**Quick Tips**:
		1. Remember 'Inhibin Inhibits FSH': This helps link the hormone to its primary function.
		2. Associate Sertoli cells (males) and granulosa cells (females) with inhibin production.

A SUBRAMANYAM · Answer

It is secreted by the Leydig cells in males and inhibits secretion of LH.

A SUBRAMANYAM · Answer

The correct Option is "It is secreted by the Sertoli cells in males and granulosa cells in females and inhibits FSH secretion."

A SUBRAMANYAM · Answer

It is secreted by the pituitary gland and inhibits secretion of LH and FSH.

A SUBRAMANYAM · Answer

It is secreted by the corpus luteum and inhibits secretion of progesterone.

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