The Question is from neet-botany molecular-basis-of-inheritance replication, and it was created by the author NISHANTH

Question

There are special proteins that help to open up DNA double helix in front of the replication fork. These protein are

NISHANTH · Accepted Answer

## CORE INFORMATION
✓ **Answer**: B
## CONCEPT FRAMEWORK
	**Primary Concept**: DNA Replication
	**Related Topics**: Enzymes in DNA replication, DNA structure
	**Prerequisites**: Basic understanding of DNA replication process.
## SOLUTION PATHWAY
**Given Information**:
	The question asks about proteins involved in unwinding DNA during replication.
**Method & Steps**:
	1. Recall the function of enzymes involved in DNA replication.
		Reasoning: We need to know which enzyme is responsible for relaxing supercoiling and opening the DNA helix ahead of the replication fork.
		Formula/Rule: None applicable
	2. Identify the enzyme that performs the unwinding function.
		Working: DNA gyrase is the enzyme that relieves the torsional stress caused by unwinding of the DNA double helix at the replication fork.
		Key Point: DNA ligase joins DNA fragments, and DNA polymerase I fills gaps and removes RNA primers.
	3. Determine the correct answer.
		Result: DNA gyrase is the correct answer.
		Verification: Confirmed by knowledge of DNA replication enzymes.
 ## OPTION ANALYSIS
[A] :x: DNA ligase is involved in joining DNA fragments, not unwinding.
[B] ✓: DNA gyrase is the enzyme responsible for unwinding the DNA double helix ahead of the replication fork.
[C] :x: DNA polymerase I is involved in filling gaps and removing RNA primers, not unwinding.
[D] :x: The correct answer is B (DNA gyrase).
 ## LEARNING AIDS
	**Common Mistakes**:
		1.[Error 1]: Confusing DNA ligase and DNA gyrase. [How to avoid]: Remember ligase joins, gyrase unwinds.
		2.[Error 2]: Mistaking DNA polymerase for unwinding. [How to avoid]: DNA polymerases build the new strands, not unwind the helix.
	**Quick Tips**:
		1.[Helpful shortcut]: Gyrase = 'gyro' which hints at twisting and untwisting.
		2.[Memory aid]: Think of gyrase as the 'unwinding' enzyme.

NISHANTH · Answer

DNA ligase

NISHANTH · Answer

The correct Option is "DNA gyrase"

NISHANTH · Answer

DNA polymerase-I

NISHANTH · Answer

None of these

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