The Question is from neet-botany molecular-basis-of-inheritance rna-world, and it was created by the author D VINOD

Question

The RNA world hypothesis posits RNA as the primary genetic material before DNA.  Which of the following properties of RNA is LEAST supportive of this hypothesis?

D VINOD · Accepted Answer

## CORE INFORMATION
✓ **Answer**: [Option C]
## CONCEPT FRAMEWORK
	**Primary Concept**: RNA's structural and functional properties
	**Related Topics**: Genetics, molecular biology, ribozymes
	**Prerequisites**: Understanding of nucleic acids and their roles in cellular processes
## SOLUTION PATHWAY
**Given Information**:
		- RNA's ability to act as a catalyst (ribozymes)
		- RNA's role in storing genetic information
		- RNA's susceptibility to alkaline hydrolysis
		- RNA's involvement in cellular processes like translation
**Method & Steps**:
	1.	Identify the properties of RNA that support the RNA world hypothesis.
		Reasoning: The hypothesis suggests that RNA must have properties that allow it to function both as a genetic material and as a catalyst.
		Formula/Rule: N/A
	2.	Analyze the specific properties listed in the options.
		Working: 
		- Option A: RNA catalyzes reactions (ribozymes) — supportive of the hypothesis.
		- Option B: RNA stores genetic information — supportive of the hypothesis.
		- Option C: RNA's susceptibility to alkaline hydrolysis — detrimental, as it indicates instability.
		- Option D: RNA's role in translation — supportive of the hypothesis.
		Key Point: Stability is crucial for a genetic material.
	3.	Determine which property is least supportive.
		Result: Option C highlights a weakness of RNA, making it the least supportive property.
		Verification: The other properties affirm the RNA world hypothesis, while susceptibility to hydrolysis contradicts the need for stable genetic material.
## OPTION ANALYSIS
[A] ✓: [correct option Explanation] - RNA's ability to catalyze reactions supports its role as an early life form.
[B] :x: [wrong answer Explanation] - RNA storing genetic information is crucial for the RNA world hypothesis.
[C] :x: [wrong answer Explanation] - RNA's susceptibility to alkaline hydrolysis indicates it is less stable than DNA, making it the least supportive property.
[D] :x: [wrong answer Explanation] - The presence of RNA in translation processes supports its essential role in early biology.
## LEARNING AIDS
	**Common Mistakes**:
		1. Confusing the stability of genetic material: Remember that stability is key for genetic consistency.
		2. Overlooking RNA's versatility: Recognize that RNA's ability to perform multiple roles is a significant support for the hypothesis.
	**Quick Tips**:
		1. Associate ribozymes with RNA's catalytic potential to remember its dual role.
		2. Recall that instability (like susceptibility to hydrolysis) is typically a drawback for a genetic material.

D VINOD · Answer

RNA's ability to catalyze reactions (ribozymes)

D VINOD · Answer

RNA's ability to store genetic information

D VINOD · Answer

The correct Option is "RNA's susceptibility to alkaline hydrolysis"

D VINOD · Answer

The presence of RNA in key cellular processes like translation

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