Prepare for NEET Biology Molecular Basis of Inheritance with MCQs & PYQs on NEET.GUIDE. Access free practice, previous year questions, and expert explanations of DNA replication and genetics.
The Hershey-Chase experiment utilized radioactive isotopes to label different components of bacteriophages. Which of the following combinations accurately reflects the isotopes used and the components they labeled?
32P for protein and 35S for DNA
35S for both DNA and protein
32P for DNA and 35S for protein
32P for both DNA and protein
Which observation from Griffith's experiment with Streptococcus pneumoniae provided the strongest evidence for the existence of a 'transforming principle'?
Live non-virulent bacteria did not cause disease in mice.
Heat-killed virulent bacteria did not cause disease in mice.
Live virulent bacteria caused disease in mice.
Heat-killed virulent bacteria, when mixed with live non-virulent bacteria, caused the latter to become virulent.
Avery, MacLeod, and McCarty purified the 'transforming principle' identified by Griffith. Which treatment specifically abolished the transforming activity, proving its chemical nature?
Protease
Ribonuclease
Deoxyribonuclease
Lipase
In the Hershey-Chase experiment, what crucial observation confirmed that DNA, and not protein, was the genetic material injected into bacteria by bacteriophages?
Radioactive sulfur (35S) was found inside the bacterial cells, while radioactive phosphorus (32P) remained outside.
Both radioactive phosphorus (32P) and sulfur (35S) were found inside the bacterial cells.
Neither radioactive phosphorus (32P) nor sulfur (35S) were found inside the bacterial cells.
Radioactive phosphorus (32P) was found inside the bacterial cells, while radioactive sulfur (35S) remained outside.
Which characteristic of DNA makes it a more stable carrier of genetic information compared to RNA?
The presence of uracil instead of thymine
Its single-stranded structure
The presence of deoxyribose sugar instead of ribose sugar
Its susceptibility to alkaline hydrolysis
Which scientist's experiment definitively proved that DNA is the genetic material?
Hershey and Chase
Avery, MacLeod, and McCarty
Griffith
Meselson and Stahl
Which molecule carries the genetic information in bacteriophages?
DNA
RNA
Protein
Lipids
Which molecule is hypothesized to have been the primary genetic material in the RNA world?
DNA
RNA
Proteins
Lipids
What crucial role does RNA play in the RNA world hypothesis?
Only genetic information storage
Only catalysis
Both genetic information storage and catalysis
Structural support
The RNA world hypothesis proposes that RNA was the primary genetic material in early life. Which of the following properties of RNA supports this hypothesis?
RNA is more stable than DNA.
RNA can act as both a carrier of genetic information and a catalytic enzyme.
RNA is double-stranded, providing redundancy in genetic information.
RNA cannot be degraded by enzymes.
