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NEET Questions / Botany / Molecular Basis of Inheritance / Mutations
Which of the following DNA repair mechanisms is MOST likely to be involved in correcting a thymine dimer caused by UV radiation?
Base Excision Repair
Mismatch Repair
Nucleotide Excision Repair
Homologous Recombination
Which type of mutation is MOST likely to result in a protein with a completely new function?
Silent mutation
Missense mutation in a non-coding region
Frameshift mutation in a coding region
Nonsense mutation at the very end of a coding region
Which of the following mutations is MOST likely to have a drastic effect on the protein product?
A silent mutation in the middle of the gene
A missense mutation near the end of the gene
A frameshift mutation near the start codon
A nonsense mutation near the end of the gene
Nowadays, it is possible to detect the mutated gene causing cancer by allowing a radioactive probe to hybridize its complementary DNA in a clone of cells, followed by detection using autoradiography because:
mutated DNA is amplified using PCR
mutated DNA is extracted from the cells
radioactive probes inhibit the growth of mutated cells
autoradiography can visualize the growth of mutated cells
A researcher is using a radioactive probe to detect a specific gene mutation associated with a particular type of cancer. If the mutation is present, what will be observed after autoradiography?
A completely clear film
Diffuse darkening of the entire film
Uniform darkening of the entire film
Dark spots on the film at the location of the mutated gene